Summary
Sera from 716 inhabitants of the Aland archipelago were examined for hemagglutination-inhibiting antibodies with the diphasic tick-borne encephalitis virus. The antibodies were found in 13.1 per cent of the whole series. There was no significant difference in antibody rate between males and females. It was noted that the antibody rate of the population increased almost linearly with age, which indicates that the human population of the area is exposed to a relatively constant risk of infection. Great local variations in the incidence of the antibodies were found among the residents of neighboring islands. No accumulation by families could be established in the distribution of immunity, which speaks against transmission of the virus through milk in the area.
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References
Blaškovič, D. (Editor): Epidémia Encefalitídy v Rošňavskom Prírodnom Ohnisku Nákaz, Vydavatelstvo Slovenskej Akadémie Vied, Bratislava1954 (in Slovak with English, summary).
Clarke, D. H., andJ. Casals: Amer. J. trop. Med. Hyg.7, 561 (1958).
Grešiková, M.: Acta Virol.2, 188 (1958).
Oker-Blom, N.: Ann. Med. exp. Fenn.34, 309 (1956).
Oker-Blom, N., L. Kääriäinen, M. Brummer-Korvenkontio, andP. Weckström: A paper presented at the Symposium on the Biology of Viruses of the Tick-borne Encephalitis Complex, Smolenice near Bratislava, Oct. 11–14, 1960.
Oker-Blom, N., H. Strandström, andA. W. Eriksson: Papers presented at the Second International Conference on Live Poliovirus Vaccines, Washington 1960, p. 533.
Oker-Blom, N., E. I. Wallgren, andC. Öhman: Finska Läk.-Sällsk. Handl.100, 146 (1957) (in Swedish with English summary).
Salminen, A.: Ann. Med. exp. Fenn.37, 400 (1959).
Salminen, A.: Acta Virol.4, 17 (1960).
Salminen, A.: A paper presented at the Symposium on the Biology of Viruses of the Tick-borne Encephalitis Complex, Smolenice near Bratislava, Oct. 11–14, 1960.
Salminen, A.: Ann. Med. exp. Fenn.39 (1961) (in print).
Smorodintsev, A. A. (Editor): Neuroviral Infections: Etiology, Immunology and Clinics of Diphasic Viral Meningoencephalitis and of Japanese Encephalitis, Medgiz, Leningrad 1954 (in Russian).
Svedmyr, A., G. von Zeipel, B. Holmgren, andJ. Lindahl: Arch. ges. Virusforsch.8, 565 (1958).
Walker, H. M., andJ. Lev: Statistical Inference, Henry Holt and Co., New York 1960.
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This study was partly aided by grants from the Finnish State Commission for Science, the Samfundet Folkhälsan i Svenska Finland, the Sigrid Jusélius Stiftelse, and the Rockefeller Foundation.
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Salminen, A., Eriksson, A.W. & Oker-Blom, N. Hemagglutination-inhibiting antibodies in the human population of an endemic area of diphasic tick-borne meningoencephalitis. Archiv f Virusforschung 11, 215–223 (1961). https://doi.org/10.1007/BF01241687
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DOI: https://doi.org/10.1007/BF01241687