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Hemagglutination-inhibiting antibodies in the human population of an endemic area of diphasic tick-borne meningoencephalitis

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Summary

Sera from 716 inhabitants of the Aland archipelago were examined for hemagglutination-inhibiting antibodies with the diphasic tick-borne encephalitis virus. The antibodies were found in 13.1 per cent of the whole series. There was no significant difference in antibody rate between males and females. It was noted that the antibody rate of the population increased almost linearly with age, which indicates that the human population of the area is exposed to a relatively constant risk of infection. Great local variations in the incidence of the antibodies were found among the residents of neighboring islands. No accumulation by families could be established in the distribution of immunity, which speaks against transmission of the virus through milk in the area.

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This study was partly aided by grants from the Finnish State Commission for Science, the Samfundet Folkhälsan i Svenska Finland, the Sigrid Jusélius Stiftelse, and the Rockefeller Foundation.

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Salminen, A., Eriksson, A.W. & Oker-Blom, N. Hemagglutination-inhibiting antibodies in the human population of an endemic area of diphasic tick-borne meningoencephalitis. Archiv f Virusforschung 11, 215–223 (1961). https://doi.org/10.1007/BF01241687

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  • DOI: https://doi.org/10.1007/BF01241687

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