Skip to main content
SpringerLink
Log in

Etude par immunodiffusion de l'hétérogénéité du virus de l'herpes simplex

Studies on the heterogeneity of herpes simplex virus by means of immunodiffusion

  • Published:
Archiv für die gesamte Virusforschung Aims and scope Submit manuscript

Résumé

Des suspensions antigéniques brutes de cellules infectées par diverses souches d'herpesvirus hominis, comparées entre elles par la précipitation en gel au moyen de sérums de femmes enceintes, ont fourni entre autres des lignes de précipitation différentes. Les différences notées impliquent que les souches de virus diffèrent les unes des autres. Aucune corrélation n'a été établie entre ces différences et des différences biologiques ou sérologiques telles que d'autres auteurs les ont démontrées.

Summary

Crude antigenic suspensions of cells infected with various strains of herpesvirus hominis, compared with each other by the gel precipitation technique with sera of gravid women, showed differences between precipitation lines. The implication was that the strains are all different from each other. No correlation was established between these differences and biological or serological differences, observed by other authors.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Bibliographie

  1. Ashe, W. K., andH. W. Sherp: Antigenic analysis of herpes simplex virus by neutralization kinetics. J. Immunol.91, 658 (1963).

    Google Scholar 

  2. Ashe, W. K., andH. W. Sherp: Antigenio variation in herpes simplex virus isolates from successive recurrences of herpes labialis. J. Immunol.94, 385 (1965).

    Google Scholar 

  3. Blank, H.: Common viral diseases of the skin. Med. Clinics of North America43, 1401 (1959).

    Google Scholar 

  4. Dowdle, W. R., A. J. Nahmias, R. W. Harwell, andF. P. Pauls: Association of antigenic types of herpesvirus hominis with site of viral recovery. J. Immunol.99, 974 (1967).

    Google Scholar 

  5. Talke, D.: Über die serologische Beziehung zwischen B- und Herpes-simplex-Virus in der Komplementbindungsreaktion. Z. Hyg. Infekt. Krkht.150, 185 (1964).

    Google Scholar 

  6. Figuero, M. E., andW. E. Rawls: Biological markers for differentiation of herpesvirus strains of oral and genital origin. J. gen. Virol.4, 259 (1969).

    Google Scholar 

  7. Fine, D. L., R. S.Lake, and E. H.Ludwig: Acridine orange staining of Hep-2 cells infected with macroplaques and microplaques strains of herpesvirus. Amer. Soc. Microbiol., 69th Ann. Meeting, 1969.

  8. Florman, A., andF. W. Trader: A comparative study of pathogenicity and immunogenicity of four strains of herpes simplex. J. Immunol.55, 263 (1947).

    Google Scholar 

  9. Germanov, A. B., andM. I. Sokolov: Selection and genetic studies on mutants of herpes simplex virus sensitive to sulfated polysaccharides. Arch. ges. Virusforsch.28, 77 (1969).

    Google Scholar 

  10. Germanov, A. B., andM. I. Sokolov: Selection of herpes simplex virus producing mottled plaques in human fibroblast monolayers. Arch. ges. Virusforsch.28, 85 (1969).

    Google Scholar 

  11. Gray, A., T. Tokumaku, andT. F. McN. Scott: Different cytopathogenic effects observed in HeLa cells infected with herpes simplex virus. Arch. ges. Virusforsch.8, 59 (1958).

    Google Scholar 

  12. Hamar, M.: Über die Varianten des Herpesvirus hominis. Arch. klin. exp. Dermatol.220, 283 (1964).

    Google Scholar 

  13. Hallauer, C.: Über die Immunisierung des Zentralnervensystems mit einem nichtencephalitogenen Herpesstamm. Z. Hyg. Infekt. Krkht.119, 213 (1937).

    Google Scholar 

  14. Hampar, B., andM. A. Keehn: Cumulative changes in the antigenic properties of herpes simplex virus from persistently infected cell cultures. J. Immunol.99, 554 (1967).

    Google Scholar 

  15. Hoggan, M. D., B. Roizman, andPh. R. Roane, Jr.: Further studies of variants of herpes simplex virus that produce syncytia or pocklike lesions in cell cultures. Amer. J. Hyg.73, 114 (1961).

    Google Scholar 

  16. Jawetz, E., V. R. Coleman, andE. R. Merrill: Studies on herpes simplex virus. VII. Immunological comparison of strains of herpes simplex. J. Immunol.75, 28 (1955).

    Google Scholar 

  17. Kleger, B., andJ. E. Prier: Herpes simplex infection of the female genital tract. II. Association of CPE in cell cultures with the site of infection. J. inf. Dis.120, 376 (1969).

    Google Scholar 

  18. Munk, K., undD. Donner: Cytopathischer Effekt und Plaque-Morphologie verschiedener Herpes-simplex-Virus-Stämme. Arch. ges. Virusforsch.13, 529 (1963).

    Google Scholar 

  19. Munk, K., undH. Fischer: Fluoreszenzimmunologische Unterschiede bei Herpessimplex-Virus-Stämmen. Arch. ges. Virusforsch.15, 539 (1965).

    Google Scholar 

  20. Nahmias, A. J., andW. R. Dowdle: Antigenic and biologic differences in herpesvirus hominis. Progr. med. Virol.10, 110 (1968).

    Google Scholar 

  21. Nahmias, A. J., W. R. Dowdle, H. K. Kramer, C. F. Luce, andS. C. Manson: Antibodies to herpesvirus hominis types 1 and 2 in the rabbit. J. Immunol.102, 956 (1969).

    Google Scholar 

  22. Nasemann, Th.: Die Infektionen durch das Herpes-simplex-Virus. Jena: VEB Gustav Fischer Verlag, 1965.

    Google Scholar 

  23. Ouchterlont, O.: Antigen-antibody reactions in gels. Acta path. microbiol. scand.26, 507 (1949).

    Google Scholar 

  24. Plummer, Gr.: Serological comparison of the herpes viruses. Brit. J. exp. Path.45, 135 (1964).

    Google Scholar 

  25. Roizman, B., andPh. R. Roane, Jr.: Demonstration of a surface difference between virions of two strains of herpes simplex virus. Virology19, 198 (1963).

    Google Scholar 

  26. Schneweis, K. E.: Der cytopathische Effekt des Herpes-simplex-Virus. Stammdifferenzen, Stabilität, Einfluß von Immunserum und Beziehungen zur Pockengröße. Zbl. Bakt. I. Abt. Orig.186, 467 (1962).

    Google Scholar 

  27. Schneweis, K. E.: Serologische Untersuchungen zur Typendifferenzierung des Herpesvirus hominis. Z. Immunforsch.124, 24 (1962).

    Google Scholar 

  28. Scott, T. F. McN., andD. L. McLeod: Cellular response to infection with strains of herpes simplex virus. Ann. N. Y. Acad. Sci.81, 118 (1959).

    Google Scholar 

  29. Shubladze, A. K., T. M. Maevskaia, V. A. Anantev, andV. N. Volkova: On some features of different strains of herpes virus. I. Antigenic properties. Vop. Virus.5, 735 (1960).

    Google Scholar 

  30. Slavin, H. B., andE. Gavett: Antigenic dissimilarity between strains of herpes simplex virus. Proc. Soc. exp. Biol. (N.Y.)63, 345 (1956).

    Google Scholar 

  31. Tokumaru, T.: Studies of herpes simplex virus by the gel diffusion technique. I. Distribution of precipitating antibodies among human sera. J. Immunol.95, 181 (1965).

    Google Scholar 

  32. Wallis, C, and J. L.Melnick: Aggregation as the cause of the non-neutralizable fraction of ECHO virus type 4. Bact. Proc, 1967.

  33. Wheeler, C. E.: Herpes simplex virus. A.M.A. Arch. Dermatol.82, 391 (1960).

    Google Scholar 

  34. Wheeler, C. E.: Biologic comparison of a syncytial and small giant cell-forming strain of herpes simplex. J. Immunol.93, 749 (1964).

    Google Scholar 

  35. Wildy, P.: Recombination with herpes simplex virus. J. gen. Microbiol.13, 346 (1955).

    Google Scholar 

  36. Womack, C. R., andB. P. Hunt: Serological differences in strains of herpes simplex virus. Science120, 227 (1954).

    Google Scholar 

Download references

Author information

Author notes

  1. J. M. Garcia

    Present address: Institut für Hygiene und Medizinische Mikrobiologie der Universität Bern, Suisse

Authors and Affiliations

  1. Institut für Hygiene und Medizinische Mikrobiologie der Universität Bern, Suisse

    V. H. Bonifas

  2. Institut de Microbiologie Médicale de l'Université de Lausanne, Suisse

    J. M. Garcia & V. H. Bonifas

Authors
  1. J. M. Garcia
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. V. H. Bonifas
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Dédié au Professeur Dr. Dr. C.Hallauer à l'occasion de son 70ème anniversaire.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Garcia, J.M., Bonifas, V.H. Etude par immunodiffusion de l'hétérogénéité du virus de l'herpes simplex. Archiv f Virusforschung 31, 125–136 (1970). https://doi.org/10.1007/BF01241671

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01241671

Search

Navigation