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Autoradiographische Beobachtungen über den Einbau von3H-Uridin in herpesinduzierten Riesenzellen

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Summary

Cytological studies indicate that Herpes induced polykaryocytes often contain normal appearing nuclei. Further, virus induced DNA-synthesis was absent in about 20% of the nuclei inside of giant cells as observed by autoradiography. On the other hand, RNA-synthesis seems to be inhibited in all nuclei of such cells as evidenced by reduced3H-uridin incorporation. It is concluded that nuclear RNA-synthesis is blocked by spreading of inhibitory factors.

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Literatur

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Author notes

  1. D. Falke

    Present address: Institut für Medizinische Mikrobiologie, Johannes-Gutenberg-Universität, Deutschland

Authors and Affiliations

  1. Institut für Medizinische Mikrobiologie, Johannes-Gutenberg-Universität, Deutschland

    W. Peterknecht

Authors
  1. D. Falke
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  2. W. Peterknecht
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Falke, D., Peterknecht, W. Autoradiographische Beobachtungen über den Einbau von3H-Uridin in herpesinduzierten Riesenzellen. Archiv f Virusforschung 24, 288–291 (1968). https://doi.org/10.1007/BF01241299

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  • DOI: https://doi.org/10.1007/BF01241299

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