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Experimental studies on phlebotomus (pappataci, sandfly) fever during world war II

Conclusions

In conclusion it may be said that while the laboratory investigations on the virus or viruses of sandfly fever, which were encountered in the Mediterranean area and in the Middle East, gave us a good deal more information on the basic properties of the virus and, also, provided a supply for storage and future studies, the primary objectives of developing some method of propagating the virus outside of the human body and of a vaccine for the protection of exposed personnel, were not attained. It is, therefore, particularly fortunate that DDT was found to be so highly effective for the control ofPhlebotomus papatasi in dwellings22, and that the available mosquito repellents proved so effective in protecting those who may be exposed out of doors. Even if future efforts should not lead to the discovery of a vaccine, sandfly fever need no longer be the military problem that it had been in various operations in endemic areas in the past.

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The work reported in this communication was carried out with the aid and under the auspices of the Commission on Neurotropic Viruses, Board for the Investigation and Control of Influenza and Other Epidemic Diseases in the Army, Preventive Medicine Division, Office of The Surgeon General, United States Army. The author was on activé duty consecutively as Major and Lieutenant Colonel in the Medical Corps of the Army. The work was begun early in 1943, near the Dead Sea in Palestine, and then continued consecutively in the Commission's Laboratory in a U. S. Army Hospital outside Cairo, Egypt, at the Children's Hospital Research Foundation and the Longview State Hospital, Cincinnati, Ohio, and finally at the Rockefeller Institute at Princeton, New Jersey and at the New Jersey State Prison at Trenton.

This article was prepared as part of the medical history program of the Army, and, with certain minor modifications, will appear in the forthcoming “History of Preventive Medicine, U. S. Army Medical Department, World War II”. It is an honor and privilege to have this article published in a volume dedicated to ProfessorR. Doerr, whose classic studies revealed the most important information currently available on pappataci fever.

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Sabin, A.B. Experimental studies on phlebotomus (pappataci, sandfly) fever during world war II. Archiv f Virusforschung 4, 367–410 (1951). https://doi.org/10.1007/BF01241161

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Keywords

  • Future Study
  • Experimental Study
  • Infectious Disease
  • Human Body
  • Basic Property