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Inability of rubella virus interference to reverse the inhibition of cellular protein synthetis caused by poliovirus

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Summary

GMK-monolayers infected with rubella virus developed a strong inhibiting effect on the multiplication of poliovirus but did not yield interferon in detectable amounts. The adsorption and the eclipse of the superinfecting poliovirus was not altered, but an extensive poliovirus RNA-synthesis was prevented. A well known early event of poliovirus infection, the inhibition of host cell protein synthesis, however, occurred in rubella virus infected cells as well as in normal cells.

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Author notes

  1. R. Thomssen

    Present address: Hygiene-Institut der Universität Gröttingen, BRD

Authors and Affiliations

  1. Hygiene-Institut der Universität Gröttingen, BRD

    E. Suhrkamp & S. Bonk

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  1. R. Thomssen
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  2. E. Suhrkamp
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  3. S. Bonk
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Additional information

The work described here was supported by a grant from the Deutsche Forschungsgemeinschaft.

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Thomssen, R., Suhrkamp, E. & Bonk, S. Inability of rubella virus interference to reverse the inhibition of cellular protein synthetis caused by poliovirus. Archiv f Virusforschung 37, 62–70 (1972). https://doi.org/10.1007/BF01241151

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  • DOI: https://doi.org/10.1007/BF01241151

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