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Studies on the behavior of arboviruses in an Aedes aegypti mosquito cell line (Peleg)

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Summary

Aedes aegypti mosquito cell cultures inoculated with eastern equine encephalitis (EEE) virus, yielded at the height of infection about 50% virus-producing cells, and a calculated amount of 600 PFU per infected cell, yet CPE was not observed. Cultures co-infected with EEE and Semliki Forest (SF) viruses supported the proliferation of both viruses, but no CPE or other evidence for the enhancement of infection was manifested. The apparent absence of doubly infected cells in cultures exposed simultaneously to EEE and SF viruses suggested that the two viruses were proliferating in different target cells.

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References

  1. Peleg, J.: Growth of arboviruses in monolayers from subcultured mosquito embryo cells. Virology35, 617–619 (1968).

    Google Scholar 

  2. Casals, J., andD. H. Clarke: Arboviruses: group A, group B. In: Viral and Rickettsial Infections of Man. Fourth edition. (F. L. Horsfall andI. Tamm, eds.), pp. 583 and 606. Philadelphia and Toronto: Lippincott Company, 1965.

    Google Scholar 

  3. Peleg, J.: Inapparent persistent virus infection in continuously grownAedes aegypti mosquito cells. J. gen. Virol.5, 463–471 (1969).

    Google Scholar 

  4. Melnick, J. L., A. S. Kaplan, E. Zabin, G. Conteras, andN. W. Larkum: An epidemic of paralytic poliomyelitis characterized by dual infections with poliomyelitis and Coxsackie viruses. J. exp. Med.94, 471–492 (1951).

    Google Scholar 

  5. Tanada, Y.: Synergism between two viruses of the Armyworm,Pseudaletia unipuncta (Haworth). J. Insect Path.1, 215–231 (1959).

    Google Scholar 

  6. Fenner, F.: The biology of animal viruses. Molecular and cellular biology. Vol. 1. pp. 370–371. New York and London: Academic Press, 1968.

    Google Scholar 

  7. Rehacek, J.: Persistent infection of mosquito cell grownin vitro with Murray Valley encephalitis and Japanese encephalitis viruses. Acta virol.12, 340–346 (1968).

    Google Scholar 

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This investigation was supported by Research Grant 06-325-01 from the US Public Health Service, Bureau of State Services.

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Peleg, J. Studies on the behavior of arboviruses in an Aedes aegypti mosquito cell line (Peleg). Archiv f Virusforschung 37, 54–61 (1972). https://doi.org/10.1007/BF01241150

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  • DOI: https://doi.org/10.1007/BF01241150

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