Abstract
A study has been made of the effect of bath-applied hydrocortisone (10−4 M) on excitatory transmission of the lateral olfactory tract (LOT), a superficial pyramidal cell synapse of the rat olfactory cortex slice. Populations EPSP and IPSP were depressed for 6–12 min and were then increased (60 min) by hydrocortisone. Recovery of evoked potentials was prolonged (40–60 min) when slices were washed with normal incubation medium. Habituation of synaptic potential during LOT repeated stimulation deteriorated as a result of hydrocortisone application in perfusion solution. The data obtained were considered to represent functions of adaption of the nervous system to a stressor.
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Translated from Problemy Éndokrinologii, Vol. 34, No. 6, pp. 52–56, November–December, 1988
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Mokrushin, A.A., Bagaeva, T.R., Gerasimova, I.A. et al. Effect of hydrocortisone on synaptic transmission in surviving rat olfactory cortex slices. Neurosci Behav Physiol 19, 329–334 (1989). https://doi.org/10.1007/BF01236023
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DOI: https://doi.org/10.1007/BF01236023