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Homotopic transplantation of embryonal neocortex tissue into damaged brains of adult rats

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Literature cited

  1. M. A. Aleksandrova, “Interneuronal connections in transplantation of embryonal brain tissue into the brain of adult mammals under normal and pathological conditions,” Dokl. Akad. Nauk SSSR,278, No. 1, 220–223 (1984).

    Google Scholar 

  2. V. F. Kichigina, A. G. Bragin, and I. S. Vinogradova, “Functional integration of nerve tissue of rat in xenotransplantation into rabbit brain,” Zhurn Vyssh. Nervn. Deyat.,34, No. 5, 932–940 (1984).

    Google Scholar 

  3. V. A. Otellin, F. A. Gurchin, E. G. Gilerovich, and V. I. Gusikhina, “Transplantation of cortical tissue of human embryonal brain into brains of adult mammals,” Dokl. Akad. Nauk SSSR,281, No. 4, 952–953 (1985).

    Google Scholar 

  4. K. Yu. Reznikov, Proliferation of Brain Cells of Vertebrates Under Conditions of Normal Development of the Brain and in Brain Trauma [in Russian], Nauka, Moscow (1981).

    Google Scholar 

  5. V. V. Senatorov and G. P. Obukhova, “Features of morphofunctional organization of embryonal nerve tissue of a transplant into adult rat brain,” Fiziol. Zh. SSSR,62, No. 8, 1075–1083 (1986).

    Google Scholar 

  6. A. Björklund, M. Segal, and U. Stenevi, “Functional reinnervation of rat hippocampus by locus coeruleus implants,” Brain Res.,170, No. 3, 409–426 (1979).

    Google Scholar 

  7. G. D. Das, “Transplantation of cerebellar tissue in the cerebellum of neonate rabbits,” Brain Res,50, No. 1, 170–173 (1973).

    Google Scholar 

  8. G. D. Das, “Neural transplantation in mammalian brain; some conceptual and technical considerations,” in: Neural Tissue Transplantation Research, Springer-Verlag, New York (1983), pp. 1–64.

    Google Scholar 

  9. G. D. Das and J. Altman, “Studies on the transplantation of developing neural tissue in the mammalian brain. I. Transplantation of cerebellar slabs into the cerebellum neonate rats,” Brain Res.,38, No. 2, 233–249 (1972).

    Google Scholar 

  10. G. D. Das and B. H. Hallas, “Transplantation of brain tissue in brain of adult rat,” Experientia,34, No. 10, 1304–1306 (1978).

    Google Scholar 

  11. P. A. T. Kelly, E. H. Gage, M. Ingvar, et al., “Functional reactivation of the deafferented hippocampus by embryonic septal grafts as assessed by measurements of local glucose utilization,” Exp. Brain Res.,58, No. 3, 570–579 (1985).

    Google Scholar 

  12. D. P. Kimble, R. Bremiller, and G. Stickrod, “Fetal brain implants improve spatial maze learning in hippocampal lesioned rats,” Neurosci. Lett., Suppl. No. 21, 51 (1985).

    Google Scholar 

  13. J. F. R. König and R. A. Klippel, The Rat Brain. A Stereotaxic Atlas of the Forebrain and Lower Parts of the Brain Stem, Williams and Wilkins, Baltimore (1963).

    Google Scholar 

  14. R. Labbe, A. Firl, E. J. Mafson, and D. G. Stein, “Fetal brain transplants; reduction of cognitive deficits in rats with frontal cortex lesions,” Science,221, No.4609, 470–472 (1983).

    Google Scholar 

  15. E. R. Lewis and C. W. Cotman, “Mechanism of septal lamination in the developing hippocampus revealed by outgrowth of fibers from septal implants. III. Competitive interactions,” Brain Res.,233, No. 1, 29–44 (1982).

    Google Scholar 

  16. E. R. Lewis and C. W. Cotman, “Neurotransmitter characteristics of brain grafts; striatal and septal tissue from the same laminated input to the hippocampus,” Neuroscience,8, No. 1, 57–66 (1983).

    Google Scholar 

  17. M. Manthorpe, M. Nieto-Sampedro, S. D. Scaper, et al., “Neurotrophic activity in brain wounds of the developing rat. Correlation with implant survival in the wound cavity,” Brain Res.,267, No. 1, 57 (1983).

    Google Scholar 

  18. M. M. Mesulam, “The blue reaction product in horseradish peroxidase neurohistochemistry incubation parameters and visibility,” J. Histochem. Cytochem.,24, No. 2, 1273–1280 (1976).

    Google Scholar 

  19. M. Nieto-Sampedro, M. Manthorpe, G. Barbin, et al., “Injury induced neuronotrophic activity in adult rat brain; correlation with survival of delayed implants in the wound cavity,” J. Neurosci.,3, No. 11, 2219–2229 (1983).

    Google Scholar 

  20. M. Nieto-Sampedro, S. R. Whittemore. D. L. Needels, et al., “The survival of brain transplants is enhanced by extracts from injured brain,” Proc. Natl. Acad. Sci. USA,81, No. 19, 6250–6254 (1984).

    Google Scholar 

  21. M. M. Oblinger and G. D. Das, “Connectivity of neural transplants in adult rats: analysis of afférents and efferents of neocortical transplants in the cerebellar hemisphere,” Brain Res.,249, No. 1, 31–49 (1982).

    Google Scholar 

  22. M. M. Oblinger, B. H. Hallas, and G. D. Das, “Neocortical trasplants in the cerebellum of the rat; their afferents and efferents,” Brain. Res.,189, No. 4, 228–232 (1980).

    Google Scholar 

  23. R. T. Robertson, “Bidirectional movement of horseradish peroxidase and the demonstration of reciprocal thalamocortical connection,” Brain Res.,130, No. 3, 538–544 (1977).

    Google Scholar 

  24. A. R. Schonfeld, A. M. Heacock, and R. Katzman, “Enhancement of central cholinergic sprouting by prior injury: correlation with endogenous trophic content of hippocampus,” Brain Res.,321, No. 2, 377–380 (1984).

    Google Scholar 

  25. U. Stenevi, A. Björklund, and N. A. Svengaard, “Transplantation of central and peripheral monoamine neurons to the adult rat brain; techniques and conditions for survival,” Brain Res.,114, No. 1, 1–20 (1976).

    Google Scholar 

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Translated from Arkhiv Anatomii, Gistologii i Embriologii, Vol. 93, No. 12, pp. 5–11, December, 1987.

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Obukhova, G.P., Senatorov, V.V. & Vartanyan, G.A. Homotopic transplantation of embryonal neocortex tissue into damaged brains of adult rats. Neurosci Behav Physiol 19, 324–329 (1989). https://doi.org/10.1007/BF01236022

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