Skip to main content
Log in

The mouse smooth muscle γ actin gene is on chromosome 6

  • Brief Communication
  • Published:
Somatic Cell and Molecular Genetics

Abstract

Smooth muscle γ actin (Actg) is expressed in smooth muscle and in haploid male germ cells. In order to further characterize theActg gene, a 60-nucleotide-long isotype-specific probe was synthesized. Single bands of DNA were detected when this oligonucleotide was used to probe blots of mouse genomic DNA digested with PstI, EcoRI, KpnI, or XbaI. These results suggestActg is a single-copy gene with no detectable pseudogenes. TheActg gene was mapped to mouse chromosome 6 by Southern blot analysis of DNA isolated from 15 mouse-hamster hybrid cell lines.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Literature cited

  1. Vandekerckhove, J., and Weber, K. (1979).Differentiation 14123–133.

    PubMed  Google Scholar 

  2. Ueyama, H., Kurokawa, K., Sasaki, I., and Ueda, K. (1987).Cell. Struct. Funct. 12463–470.

    PubMed  Google Scholar 

  3. Minty, A., Alonso, S., Guenet, J.L., and Buckingham, M.E. (1983).J. Mol. Biol. 16777–101.

    PubMed  Google Scholar 

  4. Humphries, S.E., Whittali, R., Minty, A., Buckingham, M., and Williamson, R. (1981).Nucleic Acids Res. 94895–4908.

    PubMed  Google Scholar 

  5. Engel, J.N., Gunning, P.W., and Kedes, L.H. (1981).Proc. Natl. Acad. Sci. U.S.A. 784674–4678.

    PubMed  Google Scholar 

  6. Nudel, U., Katcoff, D., Zakut, R., Shani, M., Carmon, Y., Finer, M., Czosnek, H., Ginsberg, I., and Yaffe, D. (1982).Proc. Natl. Acad. Sci. U.S.A. 792763–2767.

    PubMed  Google Scholar 

  7. Schedl, T., and Dove, W.F. (1982).J. Mol. Biol. 16041–57.

    PubMed  Google Scholar 

  8. Tobin, S.L., Zulauf, E., Sanchez, F., Craig, E.A., and McCarthy, B.J. (1980).Cell 19121–131.

    PubMed  Google Scholar 

  9. Fyrberg, E.A., Kindle, K.L., Davidson, N., and Sodja, A. (1981).Cell 24107–116.

    PubMed  Google Scholar 

  10. Cleveland, D.W., Lopata, M.A., MacDonald, R.J., Cowan, N.J., Rutter, W.J., and Kirschner, M.W. (1980).Cell 2095–105.

    PubMed  Google Scholar 

  11. Soriano, P., Szabo, P., and Bernardi, G. (1982).EMBO J. 1579–583.

    PubMed  Google Scholar 

  12. Czosnek, H., Nudel, U., Baker, P.E., Pravtcheva, D.D., Ruddle, F.H., and Yaffe, D. (1983).EMBO J. 21977–1979.

    PubMed  Google Scholar 

  13. Files, J.G., Carr, J., and Hirsh, D. (1983).J. Mol. Biol. 164355–375.

    PubMed  Google Scholar 

  14. Scheller, R.H., McAllister, L.B., Crain, W.R., Durica, D.S., Posakony, J.W., Thomas, T.L., Britten, R.J., and Davidson, E.H. (1981).Mol. Cell. Biol. 3609–628.

    Google Scholar 

  15. Kim, E., Waters, S.H., Hake, L.E., and Hecht, N.B. (1989).Mol. Cell. Biol. 91875–1881.

    PubMed  Google Scholar 

  16. Bower, P.A., Yelick, P.A., and Hecht, N.B. (1987).Biol. Reprod. 37479–488.

    PubMed  Google Scholar 

  17. Denhardt, D.T. (1966).Biochem. Biophys. Res. Commun. 23641–646.

    PubMed  Google Scholar 

  18. Hoggan, M.D., Halden, N.F., Buckler, C.E., and Kozak, C.A. (1988).J. Virol. 621055–1056.

    PubMed  Google Scholar 

  19. McHugh, K.M., and Lessard, J.L. (1988).Nucleic Acids Res. 164167.

    PubMed  Google Scholar 

  20. Carroll, S.L., Bergsma, D.J., and Schwartz, R.J. (1986).J. Biol. Chem. 2618967–8976.

    Google Scholar 

  21. Ponte, P., Gunning, P., Blau, H., and Kedes, L. (1983).Mol. Cell. Biol. 31783–1791.

    PubMed  Google Scholar 

  22. Ng, R., and Abelson, J. (1980).Proc. Natl. Acad. Sci. U.S.A. 773912–3916.

    PubMed  Google Scholar 

  23. Elder, P.K., French, C.L., Subramaniam, M., Schmidt, L.J., and Getz M. (1988).Cell. Biol. 8480–485.

    Google Scholar 

  24. Erba, H.P., Eddy, R., Shows, T., Kedes, L., and Gunning, P. (1988).Mol. Cell. Biol. 81775–1789.

    PubMed  Google Scholar 

  25. Hu, M.C., Sharp, S.B., and Davidson, N. (1986).Mol. Cell. Biol. 615–25.

    PubMed  Google Scholar 

  26. Hecht, N.B., Kleene, K.C., Yelick, P.C., Johnson, P.J., Pravtcheva, D.D., and Ruddle, F.H. (1986).Cell Mol. Genet. 12203–208.

    Google Scholar 

  27. Reeves, R.H., Gearhart, J.D., Hecht, N.B., Yelick, P.C., Johnson, P.J., and O'Brien, S.J. (1989).J. Hered. 80442–446.

    PubMed  Google Scholar 

  28. Heidaran, M.A., Kozak, C.A., and Kistler, W.A. (1989).Gene 7539–46.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kim, E., Kwon, Y.K., Trasler, J.M. et al. The mouse smooth muscle γ actin gene is on chromosome 6. Somat Cell Mol Genet 16, 287–291 (1990). https://doi.org/10.1007/BF01233365

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01233365

Keywords

Navigation