Abstract
Allele frequencies for the VNTR locus D1S80 were determined in a Chinese population sample using the polymerase chain reaction and subsequent analysis of the amplified products by polyacrylamide gel electrophoresis and silver staining. A total of 18 nominal D1S80 alleles were observed in 105 unrelated Chinese. The data demonstrate that D1S80 is highly polymorphic in Chinese with a heterozygosity of 90.5%. The D1S80 frequency distribution meets Hardy-Weinberg expectations. This D1S80 data can be used in forensic analyses and paternity tests to estimate the frequency of a DNA profile in a Chinese population.
Zusammenfassung
Allelfrequenzen für den VNTR Lokus D1S80 wurden in einer Chinesischen Populationsstichprobe mittels Polymerase-Kettenreaktion und anschließender Analyse der Amplifikationsprodukte durch Polyacrylamid-Gelelektrophorese und Silberfärbung bestimmt. Insgesamt 18 nominelle D1S80 Allele wurden bei 105 unverwandten Chinesen beobachtet. Die Daten zeigen, daß D1S80 in Chinesen hochpolymorph mit einer Heterozygosität von 90.5% ist. Die D1S80 Frequenzverteilungen sind im Hardy-Weinberg-Gleichgewicht. Diese D1S80 Daten können für forensische Analysen und Vaterschaftstests zur Abschätzung eines DNA-Profils in einer Chinesischen Population herangezogen werden.
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Huang, N.E., Chakraborty, R. & Budowle, B. D1S80 allele frequencies in a Chinese population. Int J Leg Med 107, 118–120 (1994). https://doi.org/10.1007/BF01225597
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DOI: https://doi.org/10.1007/BF01225597