Summary
Allele frequencies obtained by RFLP (Restriction Fragment Length Polymorphism) analysis using the VNTR (Variable Number Tandem Repeats) single locus probes MS1, MS31, MS43a and YNH24 onHinfI-restricted DNA in a Greenland Eskimo (155 individuals) and a Danish Caucasian (616 individuals) population sample are reported. For MS1 the frequency distributions were almost identical whereas minor but significant differences were seen for the other 3 probes. The distribution of the frequencies of 139 Greenland complete DNA profiles was estimated using the Greenland and the Danish database. The average profile frequencies obtained with the Greenland database were approximately 10 times higher than the estimates obtained with the Danish database.
Zusammenfassung
Die Allel-Frequenzen von RFLP (Restriktions-Fragmentlängen-Polymorphismen), nachgewiesen mit den VNTR (Variable Number of Tandem Repeats) Single-Locus Proben MS1, MS31, MS43a und YNH24 anHinfI-gespaltene DNA einer Populationsstichprobe von Grönland-Eskimos (n = 155 Individuen) und dänischen Kaukasiern (n = 616 Individuen) werden mitgeteilt. Für MS1 sind die Frequenz-Verteilungen nahezu identisch, während geringere, aber signifikante Unterschiede bei den anderen drei Sonden zu beobachten sind. Die Verteilung der Frequenzen der 139 kompletten Grönland-DNA-Profile wurde bestimmt mit Hilfe der grönländischen und dänischen Datenbank. Die durchschnittlichen Profil-Frequenzen, welche mit Hilfe der grönländischen Datenbank erhalten wurden, waren ungefähr 10-fach höher als jene unter Verwendung der dänischen Datenbank.
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Eriksen, B., Svensmark, O. DNA polymorphism in Greenland. Int J Leg Med 106, 254–257 (1994). https://doi.org/10.1007/BF01225415
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DOI: https://doi.org/10.1007/BF01225415