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Prenatal paternity testing with DNA analyses

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Summary

Two PCR amplified loci and 3 single locus DNA probes were applied in a paternity case in which a married woman became pregnant after being raped. DNA analysis were performed using samples from the woman, her husband and amniotic fluid cells taken during the 16th week of pregnancy. The combined probability of paternity for her husband was calculated as 0.999997107. The application of PCR analyses and single locus DNA probes were considered to be extremely informative in prenatal paternity testing.

Zusammenfassung

Zwei mit Hilfe der PCR amplifizierte Loci und 3 Single-Locus-DNA-Sonden wurden in einem Vaterschaftsfall angewandt, in welchem eine verheiratete Frau nach einer Vergewaltigung schwanger geworden war. Für die pränatal durchgeführte DNA-Analyse wurden Proben der Frau, ihres Mannes sowie in der 16. Schwangerschaftswoche gewonnene Ammnion-Zellen eingesetzt. Die kombinierte Vaterschaftswahrscheinlichkeit für den Ehemann wurde mit 0,999997107 berechnet. Die Anwendung der PCR-Analysen und der Single-Locus-DNA-Sonden erwies sich als extrem informativ für die pränatale Vaterschaftsuntersuchung.

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Natal, M., Nagae, M., Aoki, Y. et al. Prenatal paternity testing with DNA analyses. Int J Leg Med 106, 160–162 (1993). https://doi.org/10.1007/BF01225240

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  • DOI: https://doi.org/10.1007/BF01225240

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