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Synthesis markers in illegally manufactured 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine

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Summary

In this paper the isolation and identification of 12 compounds as impurities in illicit 3,4-methylenedioxyamphetamine (MDA) and 3,4-methylenedioxymethamphetamine (MDMA) is reported. Isolation of these substances is performed by preparative TLC, while identification is performed by using mass spectrometry and1H-NMR spectroscopy. A simple and rapid method for detection of these impurities in seized MDA and MDMA samples is described. The identification of the impurities can provide numerous points on which to base comparative analysis of different exhibits.

Zusammenfassung

Es wird die Isolierung und Identifizierung von 12 Synthesebeiprodukten in illegalem 3,4-Methylendioxyamphetamin (MDA) und 3,4-Methylendioxymethamphetamin (MDMA) beschrieben. Die Isolierung dieser Substanzen wird durch präparative Dünnschichtchromatographie erreicht, während die Identifizierung durch GC/MS und1H-NMR Spektroskopie erfolgt. Anschließend wird eine einfache und schnelle Methode, diese Substanzen in beschlagnahmten MDA- bzw. MDMA-Proben nachzuweisen, vorgestellt. Der Nachweis dieser Substanzen kann eine wichtige Hilfe dabei sein, eine vergleichende Analytik verschiedener Proben vorzunehmen.

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Authors and Affiliations

  1. Institut für Rechtsmedizin, Westfälische Wilhelms-Universität, v. Esmarch-Strasse 86, D-48149, Münster, Germany

    M. Bohn & G. Bohn

  2. Institut für Pharmazeutische Chemie, Westfälische Wilhelms-Universität, Hittorfstrasse 58, W-48149, Münster, Germany

    G. Blaschke

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  1. M. Bohn
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  2. G. Bohn
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  3. G. Blaschke
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Bohn, M., Bohn, G. & Blaschke, G. Synthesis markers in illegally manufactured 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine. Int J Leg Med 106, 19–23 (1993). https://doi.org/10.1007/BF01225019

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  • DOI: https://doi.org/10.1007/BF01225019

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