Abstract
We report a case of 11-year survival with carcinoma arising from a congenital choledochal cyst. A 34-year-old Japanese woman was admitted due to epigastric discomfort. Ultrasonography revealed a choledochal cyst involving a polypoid tumor. Endoscopic retrograde cholangiopancreatography revealed pancreaticobiliary maljunction in which the main pancreatic duct joined the dilated common bile duct 2 cm above the papilla of Vater. A choledochal cyst containing a polypoid tumor was resected with the regional lymph nodes. Grossly, a 2×2-cm papillary tumor was noted in the posterior wall of the choledochal cyst. Microscopically, the tumor was well-differentiated tubular adenocarcinoma invading the mucosa and fibromuscular layer. Neither anticancer chemotherapy nor radiotherapy was performed. The patient recovered uneventfully after the operation and has been well for 11 years without evidence of recurrent cancer. The good results in this patient may have been due to the early stage of the cancer.
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References
The Japanese Study Group on Pancreaticobiliary Maljunction (JSPBM), The Committee of JSPBM for Diagnostic Criteria (1994) Diagnostic criteria of pancreaticobiliary maljunction. J Hep Bil Pancr Surg 1:247–51
Todani T, Watanabe Y, Uchiyama N, Morotomi Y, Maeba T (1994) Choledochal cyst, pancreatobiliary malunion, and cancer. J Hep Bil Pancr Surg 1:247–251
Todani T, Watanabe Y, Fujii T, Toki A, Uemura S, Koike Y, Inoue T (1985) Carcinoma arising from the bile duct in choledochal cyst and anomalous arrangement of the panreatobiliary ductal union (in Japanese). Tan to Sui (J Bil Tract Pancreas) 6:525–535
Tanaka K, Mizouchi J, Yamada K, Sakamoto H, Kodama Y, Hokkoku S, Taira A, Sakoda K, Miyata S, Sibue T (1985) Congenital choledochal dilatation in adult cases (in Japanese). Tan to Sui (J Bil Tract Pancreas) 6:1295–1303
Albores-Saavedra J, Henson DE, Sobin LH (1991) Histological typing of tumours of the gallbladder and extrahepatic bile ducts. Springer, Berlin Heidelberg Tokyo New York, pp 25–26
Kuroda K, Nagai H, Morioka Y (1988) Anomalous union of the pancreaticobiliary ductal system and biliary carcinoma (in Japanese) Tan to Sui (J Bil Tract Pancreas) 9:1191–1203
Sugiura Y, Nakamura S, Iida S, Hosoda Y, Ikeuchi S, Mori S, Sugioka A, Tsuzuki T (1994) Extensive resection of the bile ducts combined with liver resection for cancer of the main hepatic duct junction: A cooperative study of the Keio Bile Duct Cancer Study Group. Surgery 115:445–451
Suzuki M, Takahashi T, Ouchi K, Matsuno S (1989) The development and extension of hepatohilar bile duct carcinoma. A three-dimensional tumor mapping in the intrahepatic biliary tree visualized with the aid of computer system. Cancer 64:658–666
Koyama K, Katoh S, Tanaka J (1987) Surgical problems of early bile duct cancer (in Japanese). Rinsho Geka (J Clin Surg) 42:1207–1213
Ogura Y, Kusuda T, Matsuda S, Mizumoto R (1989) Definition and cancer spreading in early cancer of the bile duct. Kan Tan Sui (Liver Bil Tract Pancreas) 18:883–893
Ikoma A, Nakamura N, Miyazaki T, Maeda M (1992) Double cancer of the gallbladder and common bile duct asociated with anomalous junction of pancreatico-biliary ductal system. Surgery 111:595–600
Shimoda M, Fumoto K, Ihara Y, Nakashima R, Yamagishi F, Shirasaki I, Suzuki S, Kushibushi T, Yamashita Y, Karaki Y, Tazawa K, Fujimaki M (1992) A case of carcinoma arising in the remnant choledochus 12 years after initial resection of the choledochal cyst (in Japanese). Kan Tan Sui (Liver, Bil Tract Pancreas) 24:317–324
Fujita T, Shimada H, Nakagawara G (1994) Cell kinetic study of the gallbladder epithelium, with special reference to the pancreaticobiliary maljunction. J Hep Bil Surg 1:229–235
Ohta H, Yamaguchi Y, Yamakawa O, Watanabe H, Satomura Y, Motoo Y, Okai T, Terada T, Sawabu N (1993) Biliary papillomatosis with the point mutation of K-ras gene arising in congenital choledochal cyst. Gastroenterology 105:1209–1212
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Ikoma, A., Tanaka, K., Koyanagi, H. et al. Long-term survival with carcinoma arising from a congenital choledochal cyst. J Hep Bil Pancr Surg 3, 74–77 (1996). https://doi.org/10.1007/BF01212785
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DOI: https://doi.org/10.1007/BF01212785