Skip to main content
Log in

Evaluation of different staging systems for Kaposi's sarcoma in HIV-infected patients

  • Original Papers
  • Clinical Oncology
  • Published:
Journal of Cancer Research and Clinical Oncology Aims and scope Submit manuscript

Summary

The records of 49 consecutive AIDS patients with Kaposi's sarcoma were analysed retrospectively to assess the prognostic value of the four staging systems proposed for epidemic Kaposi's sarcoma. The classifications by Krigel and Mitsuyasu do not describe exactly the characteristics of the disease, and do not give enough information on survival. Our study confirms that CD4+ cell depletion, systemic symptoms and opportunistic infections at diagnosis are the major prognostic factors and influence survival to a great extent, as shown by Krown and Chachoua.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Abbreviations

EKS:

epidemic Kaposi's sarcoma

OI:

opportunistic infections

SS:

systemic symptoms

References

  • Antinori A, Izzi I, Mencarini P, Tamburrini E (1991) Epidemic Kaposi's sarcoma: evaluation of prognostic factors and survival. In: Proceedings of VII International Conference on AIDS, Florence (abstract no. M.B.2277). Istituto Superiore Sanita, Roma

    Google Scholar 

  • Chachoua A, Krigel R, Lafleur F, Ostreicher R, Speer M, Laubenstein L, Wernz J, Rubenstein P, Zang E, Friedman-Kien A (1989) Prognostic factors and staging classification of patients with epidemic Kaposi's sarcoma. J Clin Oncol 7:774–780

    Google Scholar 

  • Friedman-Kien AE, Laubenstein LJ, Rubinstein P, Buimovici-Klein E, Marmor M, Stahl R, Spigland I, Soo Kim K Zolla-Pazner S (1982) Disseminated Kaposi's sarcoma in homosexual men. Ann Intern Med 96:693–700

    Google Scholar 

  • Hymes K, Cheung T, Greene J, Prose N, Marcus A, Ballard H, William D, Laubenstein L (1981) Kaposi's sarcoma in homosexual men. Lancet 2:598–600

    Google Scholar 

  • Krigel RL, Laubenstein LJ, Muggia FM (1983) Kaposi's sarcoma: a new staging classification. Cancer Treat Rep 67:531–534

    Google Scholar 

  • Krown SE, Metroka C, Wernz JC, AIDS Clinical Trials Group Oncology Committee (1989) Kaposi's sarcoma in the acquired immune deficiency syndrome: a proposal for uniform evaluation, response and staging criteria. J Clin Oncol 7:1201–1207

    Google Scholar 

  • Mitsuyasu RT, (1987) Clinical variants and staging of Kaposi's sarcoma. Semin Oncol 14 [Suppl 3]:13–18

    Google Scholar 

  • Mitsuyasu RT, Groopman JE (1984) Biology and therapy of Kaposi's sarcoma. Semin Oncol 11:53–59

    Google Scholar 

  • Mitsuyasu RT, Taylor JMG, Glaspy J, Fahey JL (1986) Heterogeneity of epidemic Kaposi's sarcoma. Cancer 57:1657–1661

    Google Scholar 

  • Taylor JF, Templeton AC, Vogel CL, Ziegler JL, Kyalwazi SK (1971) Kaposi's sarcoma in Uganda: a clinicopathological study. Int J Cancer 8:125–135

    Google Scholar 

  • Taylor J, Afrasiabi R, Fahey JL, Korns E, Weawer M, Mitsuyasu RT (1986) Prognostically significant classification of immune changes in AIDS with Kaposi's sarcoma. Blood 67:666–671

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Antinori, A., Izzi, I., Ammassari, A. et al. Evaluation of different staging systems for Kaposi's sarcoma in HIV-infected patients. J Cancer Res Clin Oncol 118, 635–636 (1992). https://doi.org/10.1007/BF01211811

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01211811

Key words

Navigation