Summary
Eastern Austrian regional mortality patterns of oral cancer (oral cavity, pharynx and larynx) and oesophageal, lung and urinary bladder cancer were compared to smoker rates and to liver cirrhosis mortality by type of residence: Vienna (1.7×106 inhabitants), middle towns (50 000–100 000 and 10 000–50 000 inhabitants), small towns (2000–10 000 inhabitants) and rural areas categorized by agrarian quota ≦10%, 10%–20% and >20%. The study area (Vienna, Lower Austria and Burgenland) covers 23 600 km2 with 3.23×106 inhabitants. In men, liver cirrhosis correlated negatively with smoker rates (r=−0.74, P=0.1). Deaths from oral cancer and oesophageal cancer correlated significantly with deaths from liver cirrhosis (r=0.81, P=0.03; r=0.78, P=0.04, respectively) but not with smoker rates; lung cancer and bladder cancer correlated significantly with smoker rates (r=0.91, P=0.01; r0.83, P=0.04, respectively), but not with liver cirrhosis. In women, similar urban-rural gradients for all parameters resulted in a positive correlation between liver cirrhosis and smoker rates (r=0.59, P=0.22) and a significant correlation of lung cancer with liver cirrhosis (r=0.75, P=0.05). Oral cancer correlated significantly with liver cirrhosis (r=0.83, P=0.02), but not with smoker rates; lung cancer correlated more significantly with smoker rates (r=0.92, P=0.01) than with liver cirrhosis; bladder cancer correlated positively with smoker rates (r=0.70, P=0.12). Geographical distribution of oral and oesophageal cancer in Eastern Austria seems thus to be highly subject to the prevalence of heavy drinking. Sociocultural influences upon the occurrence of these cancers seem to be mediated through drinking habits rather than through smoking habits alone.
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References
Austrian Central Statistical Office (1989) Österreichischer Todesursachenatlas 1978/84, Österr. Staatsdruckerei, Wien
Brugère J, Guenel P, Leclerc A, Rodriguez J (1986) Differential effects of tobacco and alcohol in cancer of the larynx, pharynx and mouth. Cancer 57:391–395
Elwood JM, Pearson JCG, Skippen DH, Jackson SM (1984) Alcohol, smoking, social and occupational factors in the aetiology of cancer of the oral cavity, pharynx and larynx. Int J Cancer 34:603–612
Friedl H-P (1987a) Rauchgewohnheiten der österreichischen Bevölkerung. Stat Nachr 42:328–332
Friedl H-P (1987b) Regionale Aspekte des Rauchens. Stat Nachr 42:396–397
Hakulinen T, Andersen Aa, Malker B, Pukkala E, Schou G, Tulinius H (1986) Trends in cancer incidence in the nordic countries. A collaborative study of the five Nordic Cancer Registries. The Nordic Cancer Registries, Helsinki
Jensen OM (1991) International variation in the incidence of cancer of the upper digestive and respiratory tract. Adv Otorhinolaryngol 46:124–133
La Vecchia C, Boyle P, Franceschi S, Levi F, Maisonneuve P, Negri E, Lucchini F, Smans M (1991) Smoking and cancer with emphasis on Europe.. Eur J Cancer 27:94–104
Lesch OM (1985) Chronischer Alkoholimus. Tpyen und Verlauf. Eine Langzeitstudie. Thieme, Stuttgart
Luce D, Guenel P, Leclerc A, Brugère J, Point D, Rodriguez J (1988) Alcohol and tobacco consumption in cancer of the mouth, pharynx and larynx: a study of 316 female patients. Laryngoscope 98:313–316
Mader R, Mittendorfer Ch, Pavlis L, Springer A (1981) Österreichische Trinksitten. Konsumation—Einstellung Gefährdung. Schriftenreihe des Ludwig-Boltzmann-Institutes für Suchtforschung, vol 4. Brüder Hollinek, Wien, p 39
Neumann G (1988) Bösartige Neubildungen von Lippe, Mundhöhle, Rachen, Nase, Ohr und Kehlkopf. Eine deskriptiv-epidemiologische Untersuchung. HNO 36:345–354
Schwartz D, Flamant R, Lellouch J, Denoix P (1961) Results of a French survey on the role of tobacco, particularly inhalation, in different cancer sites. J Natl Cancer Inst 29:1085–1108
Schwartz D, Lellouch J, Flamant R, Denoix P (1962) Alcohol et cancer. Résultats d'une enquête rétrospective. Rev Fr Etud Clin Biol 7:590–604
Swoboda H (1991) Epidemiology of head and neck cancer in Eastern Austria. Adv. Otorhinolaryngol 46:134–144
Swoboda H, Friedl H-P (1991) Incidence of cancer of the respiratory and upper digestive tract in urban and rural Eastern Austria. Eur J Cancer 27:83–85
Swoboda H, Neumann H, Cartellieri M (1990) Zur Epidemiologie bösartiger Neubildungen des Atmungs-und oberen Verdauungstraktes in Österreich. Laryngol Rhinol Otol (Stuttg) 69:123–130
Tuyns A (1991) Aetiology of head and neck cancer: tobacco, alcohol and diet. Adv Otorhinolaryngol 46:98–106
Tuyns AJ, Estève J, Raymond L, Berrino F, Benhamou E, Blanchet F, Boffetta P, Crosignani P, Del Moral A, Lehmann W, Merletti F, Péquinot G, Riboli E, Sancho-Garnier H, Terracini B, Zubiri A, Zubiri L (1988) Cancer of the larynx/hypopharynx, tobacco and alcohol: IARC international case-control study. Int J Cancer 41:483–491
Wynder EL, Bross IJ (1957) Aetiological factors in mouth cancer. Br Med J 1:1137–1171
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Swoboda, H., Friedl, HP. Tobacco-related cancer in relation to prevalence of drinking and smoking in Eastern Austria. J Cancer Res Clin Oncol 118, 621–625 (1992). https://doi.org/10.1007/BF01211808
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DOI: https://doi.org/10.1007/BF01211808