Abstract
A cone-mediated electroretinogram was recordable from human retinas 17–18 hours postmortem, after regeneration of visual pigments by application of 11-cis and 9-cis retinal. The cone was separated from the rod component by stimulation with flickering red light. In addition to these neuronal responses, a P2 and a slow P3 were present.
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References
Bender S, Baumann C. ERG sensitivity and rhodopsin content of isolated human retina. Pflugers Arch 1973; 341: 219–32.
Huang JC, Voaden MJ, Marshall J. Survival of structure and function in postmortem rat and human retinas: Rhodopsin, cGMP and the ERG. Curr Eye Res 1990; 9: 151–62.
Huang JC, Voaden MJ, Marshall, J, Kemp CM. Electrophysiologic characteristics of human and rat retinas in vitro. Doc Ophthalmol 1990; 76: 27–35.
Huang JC, Voaden MJ, Shallal A, Marshall J. Phototransduction and opsin synthesis in the human retina postmortem and in explant culture. Invest Ophthalmol Vis Sci 1990; 31 (suppl): 77.
Granit R. The components of the retinal cation potential in mammals and their relation to the discharge in the optic nerve. J Physiol 1933; 77: 207–39.
Arden GB. Voltage gradients across the receptor layer of the isolated rat retina. J Physiol 1976; 256: 333–60.
Ernst W, Arden GB. Separation of two PIII components in the rat electroretinogram by a flicker method. Vision Res 1972; 12: 1759–61.
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Huang, J.C., Arden, G.B., Voaden, M.J. et al. Survival of cone responses in postmortem human retina. Doc Ophthalmol 83, 91–96 (1993). https://doi.org/10.1007/BF01206206
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DOI: https://doi.org/10.1007/BF01206206