Abstract
We recorded electroretinograms from anesthetized cynomolgus monkeys by means of three monochromatic (435, 524 or 579 nm) full-field stimuli presented with a monochromatic background light. The color of the background light was changed with 29 interference filters (400–700 nm). Waveforms were analyzed by means of principal component analysis to investigate interaction between the short-wavelength cone and other systems. With the same test lights, responses were also recorded during dark adaptation after 20,000-lux full bleach. The shape of the short-wavelength cone electroretinogram changed as a function of the wavelength of monochromatic background light. The change was clearer around 500-nm background light, to which the rod system is highly sensitive. Further, short-wavelength cone responses developed during the first 15 min in the dark; however, they became smaller with the recovery of the rod system. These findings suggest that there is interaction between the shortwavelength cone and rod systems. In addition, the results of waveform analysis confirmed the interaction between the long-wavelength and middle-wavelength cone systems.
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Abbreviations
- PCA:
-
principal component analysis
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Kasuga, T., Ozaki, H. Interaction between the short-wavelength cone and rod systems in the electroretinogram of the cynomolgus monkey. Doc Ophthalmol 91, 117–127 (1995). https://doi.org/10.1007/BF01203691
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DOI: https://doi.org/10.1007/BF01203691