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Electrophysiology of the retinal pigment epithelium in central serous chorioretinopathy

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Abstract

The pathophysiology of central serous chorioretinopathy is incompletely understood but appears to involve the retinal pigment epithelium. We recorded consecutively the fast oscillation, hyperosmolarity response, acetazolamide response, and light peak from four patients with active central serous chorioretinopathy and three normal subjects to determine whether the affected eyes showed any electrophysical abnormalities. We found essentially no differences in any of the four responses between the active and the inactive eyes of the patients or between patients and normal subjects. Whatever retinal pigment epithelial dysfunction exists in central serous chorioretinopathy is unassociated with clinically evident changes in these retinal pigment epithelial electrophysiologic responses.

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Abbreviations

CSC:

central serous chorioretinopathy

References

  1. Marmor MF. New hypotheses on the pathogenesis and treatment of serous retinal detachment. Graefes Arch Ophthalmol 1988; 226: 548–52.

    Google Scholar 

  2. Marmor MF, Yao XY. Conditions necessary for the formation of serous detachment. Arch Ophthalmol 1994; 12: 30–8.

    Google Scholar 

  3. Scheider A, Nasemann JE, Lund OE. Fluorescein and indocyanine green angiographies of central serous choroidopathy by scanning laser ophthalmoscopy. Am J Ophthalmol 1993; 115: 50–6.

    Google Scholar 

  4. Marmor MF. Clinical electrophysiology of the retinal pigment epithelium. Doc Ophthalmol 1991; 76: 301–13.

    Google Scholar 

  5. Yonemura D, Kawasaki K. New approaches to ophthalmic electrodiagnosis by retinal oscillatory potential, drug-induced responses from retinal pigment epithelium and cone potential. Doc Ophthalmol 1979; 48: 163–222.

    Google Scholar 

  6. Gupta LY, Marmor MF. Sequential recording of photic and nonphotic electro-oculogram responses in patients with extensive extramacular drusen. Doc Ophthalmol 1994; 88: 49–55.

    Google Scholar 

  7. Steinberg RH, Linsenmeier RA, Griff ER. Three light-evoked responses of the retinal pigment epithelium. Vision Res 1983; 23: 1315–23.

    Google Scholar 

  8. Kawasaki K, Mukoh S, Yonemura D, Fujii S, Segawa Y. Acetazolamide-induced changes of the membrane potentials of the retinal pigment epithelial cell. Doc Ophthalmol 1986; 63: 375–81.

    Google Scholar 

  9. Mukoh S, Kawasaki K, Yonemura D, Tanabe J. Hyperosmolarity-induced hyperpolarization of the membrane potentials of the retinal pigment epithelium. Doc Ophthalmol 1985; 60: 369–74.

    Google Scholar 

  10. von Graefe A. Über die zentrale rezidivierende Retinitis. Albrecht von Graefes Arch Ophthalmol 1866: 12: 211–5.

    Google Scholar 

  11. Gass JDM. Idiopathic central serous chorioretinopathy. In: Stereoscopic atlas of macular disease 3rd ed. St Louis, Mosby; 1987; 46–59.

    Google Scholar 

  12. Yannuzzi LA. Type-A behavior and central serous chorioretinopathy. Retina 1987; 7: 111–130.

    Google Scholar 

  13. Wakabayashi K. Electrodiagnosis of primary macular dystrophies. J Juzen Med Soc 1986; 95: 399–439.

    Google Scholar 

  14. Hine JE, Kingham JD. Myelogenous leukemia and bilateral exudative retinal detachment. Ann Ophthalmol 1979; 11: 1867–72.

    Google Scholar 

  15. Bouzas EA, Scott MH, Mastorakos G, Chrousos GP, Kaiser-Kupfer MI. Central serous chorioretinopathy in endogenous hypercortisolism. Arch Ophthalmol 1993; 111: 1229–33.

    Google Scholar 

  16. Friberg TR, Eller AW. Serous retinal detachment resembling central serous chorioretinopathy following organ transplantation. Graefes Arch Ophthalmol 1990; 228: 305–9.

    Google Scholar 

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Gupta, L.Y., Marmor, M.F. Electrophysiology of the retinal pigment epithelium in central serous chorioretinopathy. Doc Ophthalmol 91, 101–107 (1995). https://doi.org/10.1007/BF01203689

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