Skip to main content
SpringerLink
Log in

Capacitance-conductance detector for high-pressure liquid chromatography. Application to alkaloids and fatty acids

  • Published:
Microchimica Acta Aims and scope Submit manuscript

Summary

A new type of detector for high-pressure liquid chromatography has been designed. This detector is equipped with a RC resonance circuit, and is similar to the capacitance detector previously reported. It is operated as a capacitance detector with nonpolar eluents; while with polar solvents, it behaves as a conductance detector. Electrolytes such as salts, acids and bases are sensitively detected. The detector was successfully used for the detection of fatty acids and alkaloids.

Zusammenfassung

Ein neuartiger Detektor für die Hochdruck-Flüssigchromatographie wurde entwickelt. Dieser ist mit einem Resonanzstromkreis ausgestattet und ähnelt dem kürzlich beschriebenen Kapazitanz-Detektor. Als solcher funktioniert er mit nichtpolaren Eluenten, während er sich mit polaren Lösungsmitteln wie ein Leitfähigkeitsdetektor verhält. Salze, Säuren und Basen werden empfindlich nachgewiesen. Das Gerät wurde zum Nachweis von Fettsäuren und Alkaloiden verwendet.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. S. Haderka, J. Chromatography52, 213 (1970).

    Google Scholar 

  2. S. Haderka, J. Chromatography57, 181 (1971).

    Google Scholar 

  3. R. Vespalec and K. Hána, J. Chromatography65, 53 (1972).

    Google Scholar 

  4. S. Haderka, J. Chromatography91, 167 (1974).

    Google Scholar 

  5. R. Vespalec, J. Chromatography108, 243 (1975).

    Google Scholar 

  6. W. F. Erbelding, Analyt. Chemistry47, 1983 (1975).

    Google Scholar 

  7. L. N. Klatt, Analyt. Chemistry48, 1845 (1976).

    Google Scholar 

  8. K. Watanabe, M. Azuma, and E. Niki, Japan Analyst26, 295 (1977).

    Google Scholar 

  9. C. Duhne and O. S. de Ita, Analyt. Chemistry34, 1074 (1962).

    Google Scholar 

  10. Y. Hashimoto and I. Mori, Nature172, 542 (1953).

    Google Scholar 

  11. R. Munier and M. Macheboeuf, C. r. acad. sci., Paris230, 1177 (1950).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Kobe Women's College of Pharmacy, Kobe, Japan

    Yohei Hashimoto, Masataka Moriyasu, Eiko Kato & Masaru Endo

  2. Rigaku Denki Co. Ltd., Tokyo, Japan

    Naohiko Miyamoto & Hiroshi Uchida

Authors
  1. Yohei Hashimoto
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Masataka Moriyasu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Eiko Kato
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Masaru Endo
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Naohiko Miyamoto
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Hiroshi Uchida
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hashimoto, Y., Moriyasu, M., Kato, E. et al. Capacitance-conductance detector for high-pressure liquid chromatography. Application to alkaloids and fatty acids. Mikrochim Acta 70, 159–167 (1978). https://doi.org/10.1007/BF01196477

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01196477

Keywords

Search

Navigation