Skip to main content
SpringerLink
Log in

A simple and sensitive catalytic method for determination of the total iron-binding capacity of blood serum

  • Published:
Microchimica Acta Aims and scope Submit manuscript

Summary

A catalytic method is proposed for determination of the total iron-binding capacity of blood serum, based on the iron-catalysed oxidation ofp-phenetidine by hydrogen peroxide. Only 0.05 ml of serum is necessary for a single determination. The results obtained by the catalytic method show good correlation with those obtained by a photometric method (with bathophenanthroline) and by atomic-absorption spectrometry.

Zusammenfassung

Eine katalytische Methode zur Bestimmung der Eisenbindungskapazität von Blutserum wurde vorgeschlagen. Sie beruht auf der Fe-katalysierten Oxydation vonp-Phenetidin durch Wasserstoffperoxid. Für eine Bestimmung werden nur 0,05 ml Serum benötigt. Die mit dieser Methode erhaltenen Ergebnisse korrelieren sehr gut mit Werten, die mittels Atomabsorption und Spectralphotometrie (Bathophenanthrolinmethode) erhalten wurden.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. W. N. M. Ramsay, J. Clin. Path.26, 691 (1973).

    PubMed  Google Scholar 

  2. S. H. Tsung, W. A. Rosenthal, and K. A. Milwski, Clin. Chem.21, 1063 (1975).

    PubMed  Google Scholar 

  3. C. Van der Heul, H. G. Van Eiyk, W. F. Wiltnik, and B. Leijnse, Clin. Chim. Acta38, 347 (1972).

    PubMed  Google Scholar 

  4. A. Alexiev, P. R. Bontchev, and D. Raykowa, Mikrochim. Acta [Wien]1974, 751.

  5. P. R. Bontchev, D. Raykowa, A. Alexiev, and D. Yankova, Clin. Chim. Acta57, 37 (1974).

    PubMed  Google Scholar 

  6. A. A. Alexiev, P. R. Bontchev, and I. Todorov, Archs. Oral Biol.18, 1461 (1973).

    Google Scholar 

  7. A. A. Alexiev, P. R. Bontchev, and V. Burdarov, Mikrochim. Acta [Wien]1976 II, 535.

    Google Scholar 

  8. C. Pronk, H. Oldenziel, and H. C. Lequin, Clin. Chim. Acta50, 35 (1974).

    PubMed  Google Scholar 

  9. D. Pavlov and P. Stanchev, Pediatria (Sofia)9, 307 (1970).

    Google Scholar 

  10. V. Butler, Clin. Chim. Acta43, 451 (1973).

    PubMed  Google Scholar 

  11. F. W. Sunderman, Human Pathol.4, 549 (1973).

    Google Scholar 

  12. Y. Y. Yeh and P. Zee, Clin. Chem.20, 360 (1974).

    PubMed  Google Scholar 

  13. R. Pancheva, Sovr. Medicina (Sofia)1975, 46.

Download references

Author information

Authors and Affiliations

  1. Department of Analytical Chemistry, Sofia University, 1 Anton Ivanov, Sofia 26, Bulgaria

    A. A. Alexiev, P. R. Bontchev & M. Khristova

Authors
  1. A. A. Alexiev
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. R. Bontchev
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. Khristova
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Alexiev, A.A., Bontchev, P.R. & Khristova, M. A simple and sensitive catalytic method for determination of the total iron-binding capacity of blood serum. Mikrochim Acta 71, 165–174 (1979). https://doi.org/10.1007/BF01196402

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01196402

Keywords

Search

Navigation