Abstract
The crystal structures of two tetracycline derivatives, 4-dedimethylaminotetracycline hydrate and 6-methylene-5-oxytetracycline hydrochloride (methacycline·HCl), were determined using X-ray intensity data measured on a diffractometer. The first compound crystallizes with two chemical formula and one water molecule per asymmetric unit. The monoclinic crystal [a=7.174(5),b=12.029(9),c=21.117(15) Å,β=93.16(6)°] shows the space groupP21. Crystals of methacycline hydrochloride are orthorhombic, space groupP212121,a=9.472(1),b=11.921(3),c=18.945(4)Å, with one molecule in the asymmetric unit.
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Kozioł, A.E., Davis, J., Palenik, R.C. et al. Structural studies of two tetracyclines: 4-dedimethylaminotetracycline hydrate and 6-methylene-5-oxytetracycline hydrochloride. Journal of Crystallographic and Spectroscopic Research 22, 493–501 (1992). https://doi.org/10.1007/BF01195412
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DOI: https://doi.org/10.1007/BF01195412