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Iontophoretic release and transport of alkaloids fromCatharanthus roseus cells in a ceramic hollow fiber reactor

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Summary

An iontophoretic device with a configuration similar to that of a single hollow fiber reactor was found to enhance the release and transport of intracellular alkaloids fromCatharanthus roseus cells. As the applied current increased from 1 to 2 milliamperes, the rate of release and transport of alkaloids almost doubled. Pretreatment of the cells with DMSO further enhanced the production.

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Authors and Affiliations

  1. Department of Chemical Engineering, West Virginia University, 26506, Morgantown, WV, USA

    H. T. Pu, R. Y. K. Yang & F. L. Saus

Authors
  1. H. T. Pu
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  2. R. Y. K. Yang
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  3. F. L. Saus
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Pu, H.T., Yang, R.Y.K. & Saus, F.L. Iontophoretic release and transport of alkaloids fromCatharanthus roseus cells in a ceramic hollow fiber reactor. Biotechnol Lett 11, 83–86 (1989). https://doi.org/10.1007/BF01192179

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  • DOI: https://doi.org/10.1007/BF01192179

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