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Zinc-positive boutons in the cerebral cortex of lizards show glutamate immunoreactivity

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Journal of Neurocytology

Summary

Zinc-positive boutons, originating in the medial cortex of lizards, exhibit glutamate immunoreactivity. This finding supports the presumed homology between lizard zinc-positive boutons and the hippocampal mossy fibres of mammals, which are also glutamate-immunoreactive and zinc-positive.

Zinc-positive boutons of lizards contain a chelatable pool of zinc located in the synaptic vesicles, as occurs in the hippocampal mossy fibres of mammals. These synaptic systems also contain glutamate, which indicates a possible simultaneous action of zinc and glutamate during synaptic transmission.

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Authors and Affiliations

  1. Catedra de Citologia e Histologia, Facultad de Ciencias Biologicas, Universidad de Valencia, Burjasot, Valencia, Spain

    F. J. Martinez-Guijarro & C. Lopez-Garcia

  2. Unidad de Biologia Celular, Facultad de Biologia, Universidad de Barcelona, Spain

    E. Soriano & J. A. Del Rio

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  1. F. J. Martinez-Guijarro
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  2. E. Soriano
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  3. J. A. Del Rio
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  4. C. Lopez-Garcia
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Martinez-Guijarro, F.J., Soriano, E., Del Rio, J.A. et al. Zinc-positive boutons in the cerebral cortex of lizards show glutamate immunoreactivity. J Neurocytol 20, 834–843 (1991). https://doi.org/10.1007/BF01191734

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  • DOI: https://doi.org/10.1007/BF01191734

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