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Automatische Natrium-Fluxometrie

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Zusammenfassung

Es wurde eine neue Apparatur zur Kurzschlußstrommessung während des aktiven Na-Transportes beschrieben. Dabei fand man zwei verschiedene Stromkurven:

  1. 1.

    die initiale instabile Phase und die

  2. 2.

    späte stabile Phase.

Durch eine Elektrolytenänderung hat man das Profil der Stromkurven geändert. Zum Beispiel dämpft Barium die instabile Phase und verländert die hohen Werte der stabilen Phase.

Mit dieser Apparatur ist es möglich, völlig automatisch mehrere Meßstellen auf einmal zu korrigieren und registrieren.

Die wichtige Rolle, die dieser Apparat in der Molekularphysiologie, -pathologie und -pharmakologie bieten kann, wird diskutiert.

Summary

A new apparatus for short-circuit measuring during active sodium transport is described. Two distinguished current curves are observed:

  1. 1.

    initial instabile phase and

  2. 2.

    stagnant stabile phase.

By modification of electrolytes we obtained considerable change in those curves. F. ex. Barium abolishes instabile phase and supports stabile phase from beginning on high values. It is possible to test simultaneously several “Na transport cells” with automatic correction and registration. The possible use of this Fluxometer in molecular physiology, pathology and pharmacology are discussed.

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Authors and Affiliations

  1. Hauptlaboratorium der Schering AG, Berlin

    H. Albertz & M. Muftic

Authors
  1. H. Albertz
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  2. M. Muftic
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Additional information

Herrn Professor Dr.Karl Junkmann zum 70. Geburtstag gewidmet.

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Albertz, H., Muftic, M. Automatische Natrium-Fluxometrie. Biophysik 4, 214–223 (1968). https://doi.org/10.1007/BF01191597

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  • DOI: https://doi.org/10.1007/BF01191597

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