, Volume 10, Issue 1, pp 39–43 | Cite as

Absorption of sodium ions from rat intestinein vivo and from a perfused isolated preparation

  • J. Gits
  • G. B. Gerber


Intestinal absorption of different amounts of Na+ was followedin vivo and in an isolated piece of small intestine perfused with bloodvia its natural route. Normal rats display saturation kinetics whereas rats dying from the G I syndrome absorb Na+ by simple diffusion. The data indicate that the perfused intestine is a system suitable to study absorption under physiological conditions.


Sodium Small Intestine Physiological Condition Intestinal Absorption Simple Diffusion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Gerber, G. B., Remy-Defraigne, J.: DNA metabolism in perfused organs. II Incorporation into DNA and catabolism of thymidine at different levels of substrate by normal and X-irradiated liver and intestine. Arch. intern. physiol. et biochem.74, 785 (1966).Google Scholar
  2. Gerber, G. B., Altman, K. I.: In: Radiation biochemistry — Vol II. Altman, K. I., Gerber, G. B., Okada, S.,Eds. New York: Acad. Press (1970).Google Scholar
  3. Gerber, G. B., Remy-Defraigne, J., Kocmierska-Grodska, D.: Der Abbau von teilweise denaturiertem Albumin im isoliert perfundierten Darm normaler und bestrahlter Ratten. Strahlentherapie139, 744 (1970).Google Scholar
  4. Gerber, G. B., Deroo, J., Mazanowska, A.: Metabolism of 5-hydroxytryptophan in isolated perfused intestine from normal and X-irradiated rats. Arch. intern. physiol. et biochem.80, 733 (1972).Google Scholar
  5. Gits, J., Gerber, G. B.: Electrolyte loss, the main cause of death from the GI syndrome (in press).Google Scholar
  6. Handbook of Physiology — Alimentary Canal — III. Intestinal absorption. (Heidel, W., Ed. Washington: American Physiological Society 1968.Google Scholar
  7. Parsons, D. S., Paterson, C. R.: Fluid and solute transport across rat colonic mucosa. Quart. J. Physiol.50, 220 (1965).Google Scholar
  8. Soergel, K. H.: Intestinal perfusion studies: values, pitfalls and limitations. Gastroenterology61, 261 (1971).Google Scholar
  9. Whalen, G. E., Harris, J. H., Geenen, J. E., Soergel, K. H.: Sodium and water absorption from the human small intestine; the accuracy of the perfusion method. Gastroenterology51, 975 (1966).Google Scholar

Copyright information

© Springer-Verlag 1973

Authors and Affiliations

  • J. Gits
    • 1
  • G. B. Gerber
    • 1
  1. 1.Euratom and Radiobiology DepartmentC.E.N./S.C.K.Mol.Belgium

Personalised recommendations