Conclusions
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1.
A pharmacological analysis showed that in the rat hypothalamus the cholinergic systems controlling ACTH secretion are localized in the mamillary region, the α-adrenergic systems in the region of the posterior and anterior hypothalamus, the β-adrenergic receptors (which evidently play an inhibitory role) in the ventromedial region of the hypothalamus.
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2.
Since the adrenocortical response to a pain stimulus after selective cutoff of the cholino- or adrenoreactive systems of the hypothalamus is equally pronounced in comparison with the control, the results that we obtained are evidence of the important role of the cholino- and adrenoreceptors of the hypothalamus primarily in maintaining the tonic phase of ACTH secretion.
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Translated from Problemy Éndokrinologii, Vol. 27, No. 3, pp. 38–43, May–June, 1981.
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Sapronov, N.S. Distribution of the hypothalamic cholinergic and adrenergic systems controlling the function of the pituitary-adrenal system. Neurosci Behav Physiol 12, 375–380 (1982). https://doi.org/10.1007/BF01189298
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DOI: https://doi.org/10.1007/BF01189298