Conclusions
-
1.
A comparison of the effects of intracellular rhythmic and associated electrostimulation on the character of spontaneous activity of individual snail neurons showed that the cells are capable of long adaptive reorganizations of the initial rhythm, which are observed only under the effect of automatic reinforcing stimulation. In this case the changes in the frequency and character of the spontaneous discharge lead to a change in the number of effects applied to the neuron.
-
2.
Minimization and maximization of autoreinforcements obtained on individual neurons during their associated intracellular stimulation are regarded as the cellular analogue of the instrumental reflex, in which spontaneous neuronal activity serves as the operant response.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature cited
N. N. Vasilevskii, Ecophysiology of the Brain [in Russian], Meditsina, Leningrad (1979).
Ya. I. Verbnyi, “Effect of enkephalins on plasticity of snail neurons,” Zh. Vyssh. Nervn.Deyat.,35, No. 2, 306 (1985).
Ya. I. Verbnyi and V. M. Vinetskii, “A simple device for compensating the stimulation artifact with recording and stimulation through one microelectrode,” Fiziol. Zh. SSSR,70, No. 11, 157 (1984).
Kh. L. Gainutdinov and M. B. Shtark, Ionic Mechanisms of Associative Learnings (Simple Nervous Systems) [in Russian], Preprint No. 243 IAE SO Akad. Nauk SSSR, Novosibirsk (1984).
T. N. Grechenko, “‘Conditioned response’ of an electrically excitable membrane of isolated neurons of the edible snail,” Zh. Vyssh. Nervn. Deyat.,34, No. 5, 982 (1984).
T. N. Grechenko and E. N. Sokolov, “Endoneuronal plasticity of isolated neurons of the edible snail,” Zh. Vyssh. Nervn. Deyat.,29, No. 5, 1093 (1979).
G. G. Zubova, A. L. Krylova, and E. N. Sokolov, “Pacemaker plasticity of the command neuron of the defense reflex of the edible snail,” Zh. Vyssh. Nervn. Deyat.,31, No. 6, 1263 (1981).
B. I. Kotlyar, V. I. Maiorov, N. O. Timofeeva, and V. V. Shul'govskii, Neuronal Organization of Conditioned Reflex Behavior [in Russian], Nauka, Moscow (1983).
E. Kandel, Cellular Basis of Behavior [Russian translation], Mir, Moscow (1980).
O. A. Maksimov and P. M. Balaban, Neuronal Mechanisms of Behavioral Plasticity [in Russian], Nauka, Moscow (1983).
B. S. Osipov, Functional Plasticity of Mollusk Neurons [in Russian], Izd. LGU, Leningrad (1980).
V. B. Partsvaniya, “Plasticity of the pacemaker mechanism,” Psikhol. Zh.,4, No. 1, 51 (1983).
V. B. Partsvaniya and N. N. Tavkhelidze, “Role of the pacemaker potential in the organization of neuronal responses,” Zh. Vyssh. Nervn. Deyat.,31, No. 6, 1286 (1981).
A. S. Ratushnyak, L. V. Voskresenskaya, T. M. Pankova, and M. B. Shtark, “‘Adaptive’ trace reaction of hippocampal neurons in a tissue culture,” Dokl. Akad. Nauk SSSR,228, No. 6, 1479 (1976).
E. N. Sokolov, Neuronal Mechanisms of Memory and Learning [in Russian], Nauka, Moscow (1981).
E. N. Sokolov, G. G. Arakelov, E. G. Litvinov, R. Martines-Soler, V. B. Partsvaniya, et. al., Neuronal Pacemaker Potential [in Russian], Metsniereba, Tbilisi (1975).
E. N. Sokolov and T. N. Grechenko, “Cellular mechanisms of memory,” in: Problems of Neurocybernetics. Neurophysiological Aspects [in Russian], Izd. RGU, Rostov-on-Don (1978), p. 97.
W. J. Davis and R. Gillete, “Neural correlate of behavioral plasticity in command neurons of Pleurobranchaea,” Science,199, No. 4330, 801 (1978).
W. T. Frazier, R. Waziri, and E. R. Kandel, “Alterations in the frequency of spontaneous activity inAplysia neurons with contingent and noncontingent nerve stimulation,” Fe. Proc.,24, No. 3, 522 (1965).
T. N. Grechenko, “Associative learning in completely isolated neurons,” Brain and Behav. Proc. 28th Intern. Congr. Physiol. Sci., Budapest, July 13–19, 1980, Oxford, Budapest (1981), p. 39.
E. N. Sokolov, “Introduction to learning in isolated neuronal structures (intracellular mechanisms of associative learning),” Brain and Behav. Proc. 28th Intern. Congr. Physiol. Sci., Budapest, July 13–19, 1980, Oxford, Budapest (1981), p. 3.
E. N. Sokolov and T. N. Grechenko, “Identified isolated command neurons: associative learning,” Cellular Analogues of Conditioning and Neuronal Plasticity, Satell. Sympos. 28th Intern. Congr. Physiol. Sci., Szeged, 1980, Oxford, Budapest (1981), p. 225.
E. N. Sokolov and T. N. Grechenko, “Pacemaker plasticity in isolated neuron,” Brain and Behav. Proc. 28th Intern. Congr. Physiol. Sic., Budapest, July 13–19, 1980, Oxford, Budapest (1981), p. 7.
E. N. Sokolov and A. O. D. Willows, “Concluding remarks on learning in isolated neuronal structures,” Brain and Behav. Proc. 28th Intern. Congr. Physiol. Sci., Budapest, July 13–19, 1980, Oxford, Budapest (1981), p. 47.
Author information
Authors and Affiliations
Additional information
Translated from Zhurnal Vysshei Nervnoi Deyatel'nosti imeni I. P. Pavlova, Vol. 36, No. 6, pp. 1108–1115, November–December, 1986.
Rights and permissions
About this article
Cite this article
Verbnyi, Y.I. Plastic changes in the spontaneous activity of snail neurons under rhythmic and associated intracellular electrostimulation. Neurosci Behav Physiol 17, 400–406 (1987). https://doi.org/10.1007/BF01188729
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF01188729