Conclusions
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1.
The opioid agonists exhibit a dose-dependent secondary reinforcing effect, detectable by the reaction of conditioned place preference in mice.
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2.
The “mu”- and “sigma”-opiate receptors participate in the realization of the secondary reinforcing effects of opioid agonists.
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Translated from Zhurnal Vysshei Nervnoi Deyatel'nosti imeni I. P. Pavlova, Vol. 36, No. 6, pp. 1069–1076, November–December, 1986.
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Zvartu, É.É., Kovalenko, V.S. Secondary reinforcing effects of opiate agonists in mice. Neurosci Behav Physiol 17, 379–386 (1987). https://doi.org/10.1007/BF01188726
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DOI: https://doi.org/10.1007/BF01188726