Conclusions
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1.
The administration of 2 μg of a cyclic enkephalin analog speeds up the development of conditioned reflexes of bilateral avoidance without significantly affecting their retention and reproduction. In this case retention and reproduction of conditioned reflexes of so-called passive avoidance deteriorate.
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2.
A change in the functional state of the monoaminergic systems of the brain modifies the influence of the cyclic enkephalin analog on the retention of conditioned reflexes of bilateral avoidance.
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3.
Administration of a cyclic enkephalin analog increases the acetylcholinesterase analog in the motor and visual cortex of the brain.
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Translated from Zhurnal Vysshei Nervnoi Deyatel'nosti imeni I. P. Pavlova, Vol. 35, No. 4, pp. 710–717, July–August, 1985.
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Getsova, V.M., Malikova, N.A., Damitov, S.K. et al. Influence of a cyclic enkephalin analog on learning and memory in mice. Neurosci Behav Physiol 16, 370–376 (1986). https://doi.org/10.1007/BF01185366
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DOI: https://doi.org/10.1007/BF01185366