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Crystal and molecular structure of 1-(2-isopropylcarbamoylpropan-2-ylamino) 3-(1-naphthyloxy)propan-2-ol (C20H28N2O3)

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Abstract

The crystal structure of the title compound has been determined with three-dimensional MoKα X-ray diffraction data. The space group and unit-cell parameters are:P21/c,a=8.610(3) Å,b=13.516(5) Å,c=16.818(5) Å,β=94.95(3)° andV=1950.0(7) Å3. The structure was solved by direct methods, and refined by full-matrix least-squares techniques toR=0.0608 andR w=0.0648. The compound is a derivative of the popularβ-adrenolytic propranolol, and in the propanol part of the side chain shows the typicalgauche conformation.

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Authors and Affiliations

  1. Institute of General Chemistry, Poland

    M. W. Wieczorek & G. D. Bujacz

  2. Institute of Technical Biochemistry, Poland

    E. Galas

  3. Institute of Organic Chemistry, Technical University of Lodz, Zwirki 36, 90-924, Lodz, Poland

    J. Zjawiony & A. Wojciechowska

Authors
  1. M. W. Wieczorek
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  2. G. D. Bujacz
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  3. E. Galas
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  4. J. Zjawiony
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  5. A. Wojciechowska
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Wieczorek, M.W., Bujacz, G.D., Galas, E. et al. Crystal and molecular structure of 1-(2-isopropylcarbamoylpropan-2-ylamino) 3-(1-naphthyloxy)propan-2-ol (C20H28N2O3). Journal of Crystallographic and Spectroscopic Research 19, 883–892 (1989). https://doi.org/10.1007/BF01185354

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  • DOI: https://doi.org/10.1007/BF01185354

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