Skip to main content
SpringerLink
Log in

Hydrogen ion role in active transport of potassium and sodium through neuron membranes in the snailHelix pomatia

  • Published:
Neuroscience and Behavioral Physiology Aims and scope Submit manuscript

Abstract

The Na and K flux along the concentration gradients and the active transport of these ions through the neuron membrane of the snailHelix pomatia were investigated as functions of pH of the medium by Conway's method (1, 2) of loading cells with Na ions in the cold followed by restoration of the ionic composition by incubation at room temperature. The pH-maximum of the ion migration rates along concentration gradients was in the acid region for Na flux and in the neutral or weakly alkaline region for K. Hydrogen has an inhibitory effect on active ion transport. Analysis of the results by the Lineweaver-Burk method showed that the inhibition of the K influx is competitive, and that of the Na efflux noncompetitive.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. CONWAY, E. J. and M. MULLANEY. In: Membrane Transport and Metabolism. New York, Academic Press, 1961, p. 117.

    Google Scholar 

  2. CONWAY, E. J., R. P. KERNAN and G. A. ZADUNAISKI. J. Physiol. (London) 155: 263, 1961.

    Google Scholar 

  3. ZELENSKAYA, V. S., T. N. OLEINIKOVA and Z. A. SOROKINA. In: Physiology and Biochemistry of Invertebrates. Leningrad, Nauka, 1968, p. 84.

    Google Scholar 

  4. MAIZELS, M. J. Physiol. (London) 108:247, 1949.

    Google Scholar 

  5. KEYNES, R. D. J. Physiol. (London) 114:119, 1951; Proc. Roy. Soc. Ser. B. 142: 359, 1954.

    Google Scholar 

  6. KHODOROV, B. I. The Problem of Excitability. Leningrad, Meditsina, 1969.

    Google Scholar 

  7. CALDWELL, P. C. J. Physiol. (London) 142:22, 1958.

    Google Scholar 

  8. SOROKINA, Z. A. Tsitologiya. 3:48, 1961.

    Google Scholar 

  9. WESPI, H. H. Pflügers. Arch. Gesamte Physiol. Menschen Tiere. 306:262, 1969.

    Google Scholar 

  10. HOLMES, O. Arch. Intern. Physiol. 70:211, 1962.

    Google Scholar 

  11. KIRSENKO, O. V. In: Protoplasmic Membranes and their Functional Role. Kiev, Naukova Dumka, 1965, p. 180.

    Google Scholar 

  12. MATSUI, H. and A. SCHWARTZ. Biochim. Biophys. Acta. 128:16, 1966.

    Google Scholar 

  13. SHAMOO, Y. E. and W. A. BRODSKY. Biochim. Biophys. Acta. 203:111, 1970.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Physiology, Ukrainian Academy of Sciences, Kiev

    Z. A. Sorokina

Authors
  1. Z. A. Sorokina
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sorokina, Z.A. Hydrogen ion role in active transport of potassium and sodium through neuron membranes in the snailHelix pomatia . Neurosci Behav Physiol 5, 291–296 (1972). https://doi.org/10.1007/BF01183101

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01183101

Keywords

Search

Navigation