Conclusions
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1.
Intraventricular injections of rats with 20 μliter of brain-specific proteins of the basic S-100 fraction in a concentration of 3 mg/ml (but not 1 mg/ml) significantly facilitates formation of predatory aggression of animals (killing of mice induced by food deprivation and social isolation).
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2.
This effect is evoked only by the whole S-100 molecule, but not its fragments.
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3.
Administration of the minor S-100 fraction, ablumin, and total rat brain proteins did not exert an influence on predatory aggression of animals.
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Translated from Zhurnal Vysshei Nervnoi Deyatel'nosti imeni I. P. Pavlova, Vol. 36, No. 3, pp. 502–506, May–June, 1986.
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Saidakhmetova, A.S., Rylov, A.L., Dolgov, O.N. et al. Predatory aggression of rats after intraventricular administration of individual brain-specific proteins of group S-100 and their peptide fragments. Neurosci Behav Physiol 17, 316–320 (1987). https://doi.org/10.1007/BF01183061
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DOI: https://doi.org/10.1007/BF01183061