Abstract
Changes in the heart rate were studied during stimulation of the effector nuclei of the vagus nerves — the dorsal vagal nucleus and the nucleus ambiguus — in anesthetized and unanesthetized cats. If groups of neurons, stimulation of which in anesthetized cats causes slowing of the heart, were stimulated in unanesthetized cats under conditions of free behavior, the heart rate was increased. Pharmacologicalβ- adrenergic receptor blockade by injection of Obsidan or Inderal (propranolol) demonstrated the parasympathetic nature of these effects. The fact that that they are parasympathetic in nature was also confirmed by the character of the response: its short latent period and rapid disappearnce of the effect after removal of the stimulation.
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Literature cited
V. I. Ionavichute, G. E. Samonina, and M. G. Udel'nov, Usp. Fiziol. Nauk,3, 3 (1972).
K. A. Smirnov, Fiziol. Zh. SSSR,54, 1406 (1968).
N. A. Sokolova, “Organization of parasympathetic inhibitory and acceleratory influences in extracardiac pathways and in the intracardiac nervous system,” Author's Abstract of Dissertation, Moscow (1974).
M. G. Udel'nov, Nervous Regulation of the Heart [in Russian], Moscow State University, Moscow (1961).
M. G. Udel'nov, The Physiology of the Heart [in Russian], Moscow University Press, Moscow (1975).
B. M. Fedorov, N. K. Saradzhev, and N. A. Podrezova, Fiziol. Zh. SSSR,60, 948 (1974).
A. L. Berman, The Brain Stem of the Cat, Univ. Wisconsin Press, Madison (1968).
F. R. Calaresu and J. W. Pearce, J. Physiol. (London),176, 241 (1965).
V. Carson and B. M. Wenzel, J. Comp. Physiol.,87, 449 (1974).
C. Y. Chai, J. Y. Mu, and J. R. Brobeck, Am. J. Physiol.,209, 301 (1965).
Y. B. S. Cobb and H. M. Santer, J. Physiol. (London),230, 561 (1973).
C. G. Gunn, G. Sevelius, M. J. Puiggari, and F. K. Myers, Am. J. Physiol.,214, 258 (1968).
R. L. Hamlin, W. W. Klepinger, K. W. Gilpin, and C. R. Smith, Am. J. Physiol.,222, 976 (1972).
T. L. Iano, M. N. Levy, and M. H. Lee, Am. J. Physiol.,224, 997 (1973).
J. T. Ponessa and C. N. Peiss, Federat. Proc.,26, 717 (1967).
A. M. Scher and A. C. Young, Am. J. Physiol.,218, 780 (1970).
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Translated from Fiziologicheskii Zhurnal SSSR imeni I. M. Sechenova, Vol. 62, No. 3, pp. 382–386, March, 1976.
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Dugin, S.F., Zakharov, S.I., Samonina, G.E. et al. Effects of electrical stimulation of vagal nuclei in anesthetized and unanesthetized cats. Neurosci Behav Physiol 8, 317–320 (1977). https://doi.org/10.1007/BF01182908
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DOI: https://doi.org/10.1007/BF01182908