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Regulation of genetic activity of thyroid hormones. I. Effect of purified cytoplasmic hormonereceptor complex on the template activity of chromatin

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Conclusions

  1. 1.

    A complex of thyroxine with purified cytoplasmic receptorin vitro increases the template activity of chromatin, increasing the number of transcription initiation sites.

  2. 2.

    The cytoplasmic thyroxine receptor and the hormone, tested separately, do not exhibit pronounced acceptor properties.

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Authors and Affiliations

  1. Institute of Biochemistry, Academy of Sciences of the Uzbek SSR, Tashkent

    A. Abdukarimov, A. T. Adylova & M. Z. Kkhan

  2. Zoological Division of Poona University, Poona, India

    A. Abdukarimov, A. T. Adylova & M. Z. Kkhan

Authors
  1. A. Abdukarimov
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  2. A. T. Adylova
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  3. M. Z. Kkhan
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Translated from Problemy Éndokrinologii, Vol. 27, No. 1, pp. 50–53, January–February, 1981.

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Abdukarimov, A., Adylova, A.T. & Kkhan, M.Z. Regulation of genetic activity of thyroid hormones. I. Effect of purified cytoplasmic hormonereceptor complex on the template activity of chromatin. Neurosci Behav Physiol 11, 447–449 (1981). https://doi.org/10.1007/BF01182795

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  • DOI: https://doi.org/10.1007/BF01182795

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