Summary
-
1.
The syntheses of cis-1,2,6-trimethyl-4-piperidone and of the two corresponding epimeric secondary alcohols were carried out, and the configurations of these compounds were proved.
-
2.
The reaction of phenyllithium with cis-1,2,6-trimethyl-4-piperidone was studied. The two epimeric 1,2,6-trimethyl-4-phenyl-4-piperidinols and their propionic esters were prepared.
Similar content being viewed by others
Literature cited
I. N. Nazarov, N. S. Prostakov, and N. I. Shvetsov, Zhur. Obshch. Khim.26, 2798 (1956).
I. N. Nazarov and V. A. Rudenko, Izvest. Akad. Nauk SSSR, Otdel. Khim. Nauk 6, 610 (1948).
I. N. Nazarov and S. M. Makin, Zhur. Obshch. Khim.27, 94 (1957).
C. Mannich, Arch. Pharm.272, 323 (1934); Chem. Abs.28, 4059 (1934).
F. Arndt, B. Eistert, H. Scholz, and E. Aron, Ber.69, 2373 (1936).
K. N. Campbell, J. F. Acherman, and B. K. Campbell, J. Org. Chem.15, 337 (1950).
I. N. Nazarov and R. I. Kruglikova, Zhur. Obshch. Khim.27, 346 (1957).
K. Morsch, Monatsch.60, 63 (1932).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Nazarov, I.N., Sorokin, O.I. Synthetic anesthetics. Russ Chem Bull 9, 813–818 (1960). https://doi.org/10.1007/BF01179180
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF01179180