Summary
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1.
Copolycondensation of N-carboxyglycine anhydride and glycine ethyl, ester was carried out in the mass and in solution for various relative amounts of monomers. The chemical compositions of the products were studied.
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2.
Copolycondensation proceeds under conditions of mutual initiation. No N-carboxyglycine or free peptides were detected in the copolycondensation products, but peptide esters and various amounts of piperazinediones were present.
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3.
It is suggested that the peptide chain grows from the amino end.
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Literature cited
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Poroshin, K.T., Kozarenko, T.D. & Khurgin, Y.I. Kinetics and chemistry of the polycondensation esters ofα-amino acids Communication 4. Copolycondensation of glycine ethyl ester and N-carboxyglycine anhydride. Russ Chem Bull 5, 1543–1545 (1956). https://doi.org/10.1007/BF01177537
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DOI: https://doi.org/10.1007/BF01177537