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Formylation of 1,2,3,4-tetrahydro-2,4,5-trimethylpyrrolo-1-2,c]pyrimidine. Its conversions to the 7-formyl derivative with opening of the tetrahydropyremidine ring

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

We have optimized the method for obtaining 1,2,3,4-tetrahydro-2,4,5-trimetkylpyrrolo[1,2-c]pyrimidine. We carried out the reactions of quaternization, forinylation, and opening of the tetrahydropyrinddine ring of its 7-formyl derivative and the oxime of this carbonyl compound.

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References

  1. N. S. Prostakov, A. V. Varlamov, T. N. Borisova, and N. D. Sergeeva, Khim. Geterotsikl. Soedin., No. 9, 1286 (1987).

  2. S. E. Korostova, S. G. Shevchenko, E. A. Polubentsov, A. I. Mikhaleva, and B. A. Trofimov, Khim. Geterotsikl. Soedin., No. 6, 774 (1989).

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  4. A. É. Aliev, A. A. Sinitsyna, T. N. Borisova, I. A. Stazharova, N. S. Prostakov, and A. V. Varlamov, Khim. Geterotsikl. Soedin., No. 1, 75 (1993).

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Authors
  1. T. N. Borisova
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  2. A. É. Aliev
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  3. E. A. Sorokina
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  4. A. A. Sinitsyna
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  5. A. V. Varlainov
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Additional information

Russian University of International Friendship, Moscow 117923. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 534–539, April, 1995. Original article submitted March 14, 1995.

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Borisova, T.N., Aliev, A.É., Sorokina, E.A. et al. Formylation of 1,2,3,4-tetrahydro-2,4,5-trimethylpyrrolo-1-2,c]pyrimidine. Its conversions to the 7-formyl derivative with opening of the tetrahydropyremidine ring. Chem Heterocycl Compd 31, 468–473 (1995). https://doi.org/10.1007/BF01177020

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  • DOI: https://doi.org/10.1007/BF01177020

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