Skip to main content
Log in

On the occurrence of Schwann cells within the normal central nervous system

  • Published:
Journal of Neurocytology

Summary

The presence of Schwann cells and P.N.S. myelin are reported in subpial areas of apparently normal spinal cord from one control rabbit, two experimental rabbits and one experimental guinea pig. These P.N.S. elements exerted no adverse effects upon local C.N.S. components. The occurrence of ectopic Schwann cells in the normal C.N.S. has also been reported elsewhere in studies on normal human spinal cord tissue. The propensity for Schwann cells to reside in the normal C.N.S. of several species makes it necessary for experiments and hypotheses on the aetiology of Schwann cell invasion into the abnormal C.N.S. to take the present phenomenon into consideration.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Adelman, L. S. andAronson, S. M. (1972) Intramedullary nerve fiber and Schwann cell proliferation within the spinal cord (Schwannosis).Neurology 17, 726–31.

    Google Scholar 

  • Blakemore, W. F. (1975) Remyelination by Schwann cells of axons demyelinated by intraspinal injection of 6-aminonicotinamide in the rat.Journal of Neurocytology 4, 745–57.

    PubMed  Google Scholar 

  • Blakemore, W. F. andPatterson, R. C. (1975) Observations on the interrelation of Schwann cells and astrocytes following X-irradiation of neonatal rat spinal cord.Journal of Neurocytology 4, 573–85.

    PubMed  Google Scholar 

  • Bunge, M. B., Bunge, R. P., Peterson, E. R. andMurray, M. R. (1967) A light and electron microscope study of long term organized cultures of rat dorsal root ganglia.Journal of Cell Biology 32, 439–66.

    PubMed  Google Scholar 

  • Ghatak, H., Hirano, A., Doron, Y. andZimmerman, H. M. (1973) Remyelination in MS with peripheral type myelin.Archives of Neurology 29, 262–67.

    PubMed  Google Scholar 

  • Gilmore, S. A. andDuncan, D. (1968) On the presence of peripheral-like nervous and connective tissue within irradiated spinal cord.Anatomical Record 160, 675–90.

    PubMed  Google Scholar 

  • Hirano, A., Zimmerman, H. M. andLevine, S. (1969) Electron microscopic observations of peripheral myelin in a CNS lesion.Acta Neuropathologica (Berlin) 12, 348–65.

    Google Scholar 

  • Peters, A., Palay, S. L. andWebster, de F. (1970)The fine structure of the nervous system: The cells and their processes. Harper and Row: New York.

    Google Scholar 

  • Raine, C. S. andWiśniewski, H. (1970) On the occurrence of microtubules within mature astrocytes.Anatomical Record 167, 303–8.

    PubMed  Google Scholar 

  • Schoene, W. C., Leith, J. D., Behan, P. O. andGeschwind, N. (1974) Simultaneous occurrence of multiple sclerosis and hypertrophic neuropathy. Light, electron microscopic, immunologic and clinical study.Journal of Neuropathology and Experimental Neurology 33, 190.

    Google Scholar 

  • Snyder, D. H., Valsamis, M. P., Stone, S. H. andRaine, C. S. (1975) Progressive and reparatory events in chronic experimental allergic encephalomyelitis.Journal of Neuropathology and Experimental Neurology 34, 209–21.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Raine, C.S. On the occurrence of Schwann cells within the normal central nervous system. J Neurocytol 5, 371–380 (1976). https://doi.org/10.1007/BF01175122

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01175122

Keywords

Navigation