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Ruthenium(III) ion complexes with nucleotides

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Summary

Complexes of adenosine-5′-monophosphate (5′-AMP), guanosine-5′-monophosphate (5′-GMP), inosine-5′-monophosphate (5′-IMP) and cytidine-5′-monophosphate (5′-CMP) with ruthenium trichloride have been prepared and studied by i.r. spectroscopy, diffuse reflectance spectra and magnetochemical measurements.

All complexes are probably polymeric as indicated by their insolubility in polar solvents.

The i.r. spectra suggest that the ruthenium(III) ion interacts with the ligands through N(7) of the purine mononucleotides and through N(3) of the pyrimidine mononucleotide from one side and with the phosphate group of another mononucleotide molecule from another side. The formation of hydrogen bonds reinforces the interaction.

The complexes have normal magnetic moments close to the spin-only value. The electronic spectra confirm their octahedral structure.

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References

  1. L. G. Marzilli,Progress in Inorg. Chem.,23, 255 (1977).

    Google Scholar 

  2. A. J. Thompson,Platinum Met. Rev.,21, 2 (1977).

    Google Scholar 

  3. M. J. Cleare and P. C. Hydes in H. Sigel (Ed.)Metal Ions in Biological Systems, vol. 11, Marcel Dekker, N.Y. 1980, p. 2.

    Google Scholar 

  4. S. Mansy, R. S. Tobias,Biochem.,14, 2952 (1975).

    Google Scholar 

  5. G. L. Eichhorn in H. Sigel (Ed.)Metal Ions in Biological Systems, vol. 10, Marcel Dekker, N.Y. 1979, p. 1.

    Google Scholar 

  6. B. Rosenberg, E. Renshaw, L. Van Camp, J. Hartwick, J. Drobnik,J. Bacteriol.,93, 716 (1967).

    PubMed  Google Scholar 

  7. T. Giraldi, G. Sava, G. Bertoli, G. Menstroni, G. Zassinovich,Cancer Research,37, 2662 (1977).

    PubMed  Google Scholar 

  8. G. Subramanian, J. G. McAfee,J. Nucl. Med.,11, 365 (1970).

    Google Scholar 

  9. K. Mizukawa, G. Yamamoto, T. Tamai, M. Tanabe, M. Yamato,Radioisotopes,27, 19 (1978).

    Google Scholar 

  10. M. J. Clarke, M. Buchbinder, A. D. Kelman,Inorg. Chim. Acta,27, L87 (1978).

    Google Scholar 

  11. M. J. Clarke and H. Taube,J. Am. Chem. Soc.,96, 5413 (1974).

    Google Scholar 

  12. M. J. Clarke,Inorg. Chem.,16, 738 (1977).

    Google Scholar 

  13. M. J. Clarke,J. Am. Chem. Soc.,100, 5068 (1978).

    Google Scholar 

  14. B. T. Khan and A. Mehmood,J. Inorg. Nucl. Chem.,40, 1938 (1978).

    Google Scholar 

  15. B. T. Khan, M. R. Somayajulu, M. M. Taquikhan,J. Inorg. Nucl. Chem.,40, 1251 (1977).

    Google Scholar 

  16. E. B. M. deJong, H. M. J. Goldschmidt, A. C. C. VanAlphen, J. A. Loog,Clin. Chem.,26, 1233 (1980).

    PubMed  Google Scholar 

  17. E. P. Diamandis, C. E. Efstathiou, T. P. Hadjiioannou,Clin. Chem.,28, 254 (1982).

    PubMed  Google Scholar 

  18. H. Nelson and J. F. Villa,J. Inorg. Nucl. Chem.,41, 1388 (1979).

    Google Scholar 

  19. M. Ogawa, Y. Urata, T. Sakaguchi,Japan Analyst,20, 36 (1971).

    Google Scholar 

  20. T. Shimanouchi, M. Tsuboi, T. Kyoguku,Adv. Chem. Phys.,7, 435 (1964).

    Google Scholar 

  21. A. D. Collins, P. de Meester, D. M. L. Goodgame, A. C. Skapski,Bioch. Bioph. Acta,402, 1 (1975).

    Google Scholar 

  22. N. Katsaros,Transition. Met. Chem.,7, 72 (1982).

    Google Scholar 

  23. N. Katsaros, E. Vrachnou-Astra, J. Konstantatos,J. Inorg. Biochem.,16, 227 (1982).

    PubMed  Google Scholar 

  24. A. Grigoratou and N. Katsaros,J. Inorg. Biochem.,24, 147 (1985).

    Google Scholar 

  25. G. R. Clark, J. D. Orbell, K. Aoki,Acta Crystallogr.,B 34, 2119 (1978).

    Google Scholar 

  26. J. M. Fletcher, W. E. Gardner, A. C. Fox, G. Topping,J. Chem. Soc. (A), 1038 (1967).

  27. M. Ogawa and T. Sakaguchi,Yakugaku Zasshi,91, 750 (1971).

    PubMed  Google Scholar 

  28. P. de Meester, D. M. L. Goodgame, A. C. Skapski, B. T. Smith,Bioch. Bioph. Acta,340, 113 (1974).

    Google Scholar 

  29. K. Aoki,Acta Crystallogr.,B 32, 1454 (1976).

    Google Scholar 

  30. P. de Meester, D. M. L. Goodgame, T. J. Jones, A. C. Skapski,C. R. Acad. Sci. Paris, Series C,279, 667 (1974).

    Google Scholar 

  31. P. de Meester, D. M. L. Goodgame, T. J. Jones, A. C. Skapski,Biochem. J. 139, 791 (1974).

    PubMed  Google Scholar 

  32. M. Ogawa and T. Sakaguchi,Chem. Pharm. Bull.,19, 1650 (1971).

    Google Scholar 

  33. A. Aoki,Bull. Soc. Jpn.,48, 1260 (1975).

    Google Scholar 

  34. D. J. Hodgson,Progress in Inorg. Chem.,23, 211 (1977).

    Google Scholar 

  35. P. de Meester, D. M. L. Goodgame, T. J. Jones, A. C. Skapski,Bioch. Bioph. Acta, 353 (1974).

  36. M. Ogawa and T. Sakaguchi,Yakugaku Zasshi,92, 1166 (1972).

    PubMed  Google Scholar 

  37. J. K. Shiba and R. Bau,Inorg. Chem.,17, 3484 (1978).

    Google Scholar 

  38. K. Aoki,J. Chem. Soc. Chem. Comm., 748 (1976).

  39. G. R. Clark and J. D. Orbell,Acta Crystallogr.,B 34 1815 (1978).

    Google Scholar 

  40. K. Aoki,Bioch. Bioph. Acta,447, 379 (1976).

    Google Scholar 

  41. C. Preti and G. Tosi,Transition Met. Chem.,3, 17 (1978).

    Google Scholar 

  42. Y. Tanabe and S. Sugano,J. Phys. Soc. Jpn.,9, 766 (1954).

    Google Scholar 

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Authors and Affiliations

  1. Chemistry Department, Nuclear Research Center “Democritos”, Aghia Paraskevi Attikis, Athens, Greece

    Eleni Tselepi-Kalouli & Nikos Katsaros

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  1. Eleni Tselepi-Kalouli
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  2. Nikos Katsaros
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Tselepi-Kalouli, E., Katsaros, N. Ruthenium(III) ion complexes with nucleotides. Transition Met Chem 12, 467–471 (1987). https://doi.org/10.1007/BF01171667

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  • DOI: https://doi.org/10.1007/BF01171667

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