Abstract
A new method was proposed for synthesis ofD,L-5-oxoproline from N-acetyl-L-glutamic acid in weakly acid medium in the presence of water, and hydrolysis of an acetyl and cyclization and total racemization of the acid simultaneously take place. The advantage of the method is the possibility of obtaining two individual amino acids with high yields in one chemical process usingL-glutamic acid.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 39–41, January, 1995.
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Ermakova, G.A., Skachilova, S.Y. & Yurchenko, N.I. New method of synthesis ofD,L-5-oxoproline. Chem Heterocycl Compd 31, 33–34 (1995). https://doi.org/10.1007/BF01171286
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DOI: https://doi.org/10.1007/BF01171286