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Synthesis and properties of furan derivatives. 4. Synthesis of 2,5-disubstituted 1,3,4-oxadiazoles containing furan fragments

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Abstract

The condensation of hydrochloride sats of iminoesters of furan acids with hydrazides of carboxylic acids gives 2,5-disubstituted 1,3,4-oxadiazoles containing furan fragments. Such compounds are also formed in the condensation of hydrazides of 5-R-furan-2-carboxylic acids with hydrocloride salts of carboxylic acid iminoesters. The reaction of furan acids with hydrazine dihydrochloride in polyphosphoric acid gave symmetrically disubstituted 1,3,4-oxadiazoles containing furan fragments.

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Authors
  1. R. A. Karakhanov
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  2. V. I. Kelarev
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  3. V. N. Koshelev
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  4. G. V. Morozova
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  5. Ammar Dibi
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Additional information

Communication 3, see ref. [1].

I. M. Gubkin State Petroleum and Natural Gas Institute, 117917, Moscow. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 238–249, February, 1995. Original article submitted January 24, 1995.

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Karakhanov, R.A., Kelarev, V.I., Koshelev, V.N. et al. Synthesis and properties of furan derivatives. 4. Synthesis of 2,5-disubstituted 1,3,4-oxadiazoles containing furan fragments. Chem Heterocycl Compd 31, 208–218 (1995). https://doi.org/10.1007/BF01169682

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