Abstract
4-Oxo-6, 11-dihydro-4H-thieno[3′, 2′.-5,6]-pyrinudo[1, 2-b]isoquinolines have been synthesized by the reaction of o-bromo-methylphenylacetonitrile with esters of substituted 2-aminothiophene-3-carboxylic acids. They were characterized as the hydrobromides and as the fee bases. The tautonterism of the bases in DMSO solution is discussed.
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Additional information
For Communication 6. see[1].
T. G. Shevchenko Kiev University, Kiev, 252017. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 366–369, March, 1996. Original article submitted September 9, 1995.
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Kisel', V.M., Kovtunenko, V.A., Kucherenko, T.T. et al. Condensed isoquinolines. 7.* Synthesis of derivatives of the new heterocyclic system thieno[3′,2′:5,6]-pyrimido[1,2-b]isoquinoline. Chem Heterocycl Compd 32, 315–318 (1996). https://doi.org/10.1007/BF01169250
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DOI: https://doi.org/10.1007/BF01169250