Chemistry of Heterocyclic Compounds

, Volume 1, Issue 1, pp 46–48 | Cite as

Study of the reactivity of the methylene hydrogen atoms of some azolidines. III. Kinetics of the reaction of azolidones-4 with benzaldehyde

  • S. N. Baranov
  • I. D. Komaritsa


UV spectroscopy is used to study the kinetics of formation of 5-benzylideneazolidones-4. The reaction is shown to be irreversible and follows a second-order equation. The effect of various hetero atoms (sulfur, nitrogen, and oxygen) in position 1 or 2 on the methylene group reactivity of azolidones-4 is investigated. The azolidones-4 fall into two series with respect to decreasing activity of the group in acetic acid in the presence of anhydrous sodium acetate: rhodanine>2-thiohydantoin>pseudo-thiohydantoin>glycocyamidine> thiazolidinedione-2, 4>2 -thionoxazolidone-4>hydantoin>pseudo-hydantoin>oxazolidinedione-2, 4.


Hydrogen Methylene Acetic Acid Hydrogen Atom Benzaldehyde 
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  1. 1.
    S. N. Baranov, ZhOKh, 31, 512, 1961.Google Scholar
  2. 2.
    S. N. Baranov, ZhOKh, 32, 1230, 1962.Google Scholar
  3. 3.
    G. Cilento, Chem. Rev., 60, 147, 1960.Google Scholar
  4. 4.
    R. B. Woodward, R. H. Eastman, J. Am. Chem. Soc., 68, 2229, 1946.Google Scholar
  5. 5.
    J. O'Brien, Zbl., II, 1207, 1912.Google Scholar
  6. 6.
    N. P. Komar, ZhAKh, 7, 325, 1952.Google Scholar

Copyright information

© The Faraday Press, Inc. 1965

Authors and Affiliations

  • S. N. Baranov
    • 1
  • I. D. Komaritsa
    • 1
  1. 1.L'vov State Medical InstituteUSSR

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