Chemistry of Heterocyclic Compounds

, Volume 31, Issue 5, pp 577–581 | Cite as

Synthesis of N-(ω-trimethylsilylalkyl)purines under conditions of interfacial catalysis

  • É. Alksnis
  • M. Lidak
  • É. Kyjevits


A Method of synthesis of N-(ω-trimethylsilylalkyl)purines, by alkylation of potassium salts of purine bases by 3-chloropropyltrimethylsilane and chloromethyltrimethylsilanes under conditions of interfacial catalysis, has been developed. Hydroxylation of the N-allyl group by dimethylphenylsilane, which is an alternative pathway of synthesis of silicon-containing purine derivatives, has been accomplished for the first time in the purine series. The structure of the compounds obtained was established by methods of PMR and UV spectroscopy.


Spectroscopy Potassium Organic Chemistry Catalysis Alkylation 
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Copyright information

© Plenum Publishing Corporation 1995

Authors and Affiliations

  • É. Alksnis
  • M. Lidak
  • É. Kyjevits

There are no affiliations available

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