Abstract
The structure of the product of interaction of the sodium salt of 1, 2, S-trimethyl-3 formylpiperid-4-one with cyanothioacetamide was specified. It was shown that the Knoevenagel adduct formed at the first stage in basic conditions undergoes recyclization with the formation of 1, 2,3,5,6, 7, 8, 8a-octahydro-l-oxo-6, 7, 8a-trimethyl-4-cyano-2, 7-naphthyridine-3-thione, the structure of which was confirmed by the data of physicochemical methods of analysis and chemical conversions.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 512–515, April, 1996.
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Artemov, V.A., Shestopalov, A.M. & Litvinov, V.P. Synthesis of 2,7-naphthyridines by the recyclization of trimethylformyl-piperidone. Chem Heterocycl Compd 32, 445–448 (1996). https://doi.org/10.1007/BF01165908
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DOI: https://doi.org/10.1007/BF01165908