Abstract
It has been found for the first time that 2-thioxo-4-quinazolone in the presence of acid catalysts in dimethyl sulfoxide is converted to8H,15H-1, 2, 4-thiadiazolo[3, 2-b:5, 4-b′]diquinazoline-8,15-done. The reaction proceeds via oxidative cyclocondensation. The formation of this structure in preference to five other proposed isomers is substantiated using quantum-chemical methods.
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Additional information
Institute of Plant Chemistry, Academy of Sciences of the Republic of Uzbekistan, Tashkent 700170. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 845–849, June, 1996. Original article submitted November 27, 1995.
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Shakhidoyatov, K.M., Urakov, B.A., Mukarramov, N.I. et al. Oxidative cyclocondensation of thio(seleno)-amides and ureas 1. 2-thioxo-4-quinazolone. Chem Heterocycl Compd 32, 728–731 (1996). https://doi.org/10.1007/BF01164875
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DOI: https://doi.org/10.1007/BF01164875