Abstract
The synthesis of 9-substituted adenine derivatives, containing an unsaturated fragment at the end of the acyclic chain, is described; it consists of the alkylation of adenine salts with unsaturated α-haloethers, tosylates, and epoxides. It was shown that compounds of this series possess moderate antiviral activity.
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Additional information
Volgograd Medical Academy, Scientific Research Institute of Pharmacology, Volgograd 400066. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 826–830, June, 1996. Original article submitted February 14, 1995.
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Ozerov, A.A., Novikov, M.S. Synthesis of unsaturated adenine derivatives, potential inhibitors of S-adenosyl-L-homocysteine hydrolase. Chem Heterocycl Compd 32, 712–715 (1996). https://doi.org/10.1007/BF01164872
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DOI: https://doi.org/10.1007/BF01164872