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Silyl modification of biologically active compounds. 3. organosilicon derivatives of aminoalcohols in the series of tetrahydroquinoline, tetrahydroisoquinoline, and tetrahydrosilaisoquinoline

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The N-(2′-hydroxyethyl)-1, 2, 3, 4-tetrahydroquinoline, -isoquinoline, and -silaisoquinoline, and their trimethyland triethylsilyl derivatives and the corresponding methiodides were synthesized. The acute toxicity and psychotropic activity of the compounds synthesized were studied.

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References

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Authors and Affiliations

  1. Latvian Institute of Organic Synthesis, LV-1006, Riga

    É. Lukevits, I. Segal, A. Zablotskaya & S. Germane

Authors
  1. É. Lukevits
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  2. I. Segal
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  3. A. Zablotskaya
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  4. S. Germane
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 793–799, June, 1996. Original article submitted April 25, 1996.

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Lukevits, É., Segal, I., Zablotskaya, A. et al. Silyl modification of biologically active compounds. 3. organosilicon derivatives of aminoalcohols in the series of tetrahydroquinoline, tetrahydroisoquinoline, and tetrahydrosilaisoquinoline. Chem Heterocycl Compd 32, 682–688 (1996). https://doi.org/10.1007/BF01164867

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  • DOI: https://doi.org/10.1007/BF01164867

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