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Reaction of 5,5-diphenyl-2-thiohydantoin with ethyl chloroacetate: Synthesis and crystal and molecular structure of 2,3,5,6-tetrahydroimidazo-[2,1-b]-thiazol-3,6-dione

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Abstract

The crystal and molecular structure of the title compound, obtained as a result of intramolecular cyclization of 5,5-diphenyl-2-carboxymethylmercaptohydantoin, has been determined from X-ray diffractometer data. The finalR was 0.049 for 1869 reflections. The conformation of the molecule was found to approximate to the conformations of other similar compounds, but owing to the presence of a C=O group in the thiazol ring, important differences in conjugated bonds system were observed.

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References

  • Chaudhary, H. S., Panda, C. S., and Pujari, H. K. (1970)Indian J. Chem. 8, 10.

    Google Scholar 

  • Fetter, J., Horsanyi, K., Nyitrai, J., and Lempert, K. (1970)Acta Chim. Budapest 78, 325.

    Google Scholar 

  • Harhash, A. H., Elnagdi, M. H., Sobhy, E. M., and Foda, K. M. (1975)Indian J. Chem. 13, 238.

    Google Scholar 

  • Karolak-Wojciechowska, J., and Kieć-Kononowicz, K. (1987)J. Crystallogr. Spectrosc. Res. 17, 485.

    Google Scholar 

  • Karolak-Wojciechowska, J., Mikołajczyk, M., Zatorski, A., Kieć-Kononowicz, K., and Zejc, A. (1985)Tetrahedron 41, 4593.

    Google Scholar 

  • Kieć-Kononowicz, K. (1988) Unpublished results.

  • Kieć-Kononowicz, K., and Zejc, A. (1980)Pol. J. Chem. 54, 11, 2217.

    Google Scholar 

  • Kieć-Kononowicz, K., Zatorski, A., and Karolak-Wojciechowska, J. (1988)Phosphorus and Sulfur.

  • Shalaby, A. F. A., Daboun, H. A., and Abde Aziz, M. A. (1976)Z. Naturforsch. 31b, 111.

    Google Scholar 

  • Shalaby, A. F. A., Daboun, H. A., and Abdel Aziz, M. A. (1977)Z. Naturforsch. 32b, 948.

    Google Scholar 

  • Wong, M. G., Define, I. A., and Andrews, P. R. (1986)J. Med. Chem. 29, 562.

    Google Scholar 

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Authors and Affiliations

  1. Department of Pharmaceutical Chemistry, Medical Academy, Skałeczna 10, Kraków, Poland

    Katarzyna Kieć-Kononowicz

  2. Institute of General Chemistry, Technical University, Żwirki 36, 90-924, Łódź, Poland

    Janina Karolak-Wojciechowska & Witold Kwiatkowski

Authors
  1. Katarzyna Kieć-Kononowicz
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  2. Janina Karolak-Wojciechowska
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  3. Witold Kwiatkowski
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Kieć-Kononowicz, K., Karolak-Wojciechowska, J. & Kwiatkowski, W. Reaction of 5,5-diphenyl-2-thiohydantoin with ethyl chloroacetate: Synthesis and crystal and molecular structure of 2,3,5,6-tetrahydroimidazo-[2,1-b]-thiazol-3,6-dione. Journal of Crystallographic and Spectroscopic Research 18, 563–573 (1988). https://doi.org/10.1007/BF01161149

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  • DOI: https://doi.org/10.1007/BF01161149

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